- Effect of metal ions on the stability of metallothionein in the degradation by cellular fractions in vitro
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Hahn SH, Yoo OJ, Gahl WA
- KMID: 755115
- Exp Mol Med.
- 2001 Mar;33(1):32-36.
Metallothioneins (MT), small molecular weight metal binding proteins are known to play an important protective role against heavy metal toxicity, either as antioxidants or pre-oxidants. However, the mode of metabolic... -
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- Melanosomes of retinal pigment epithelium--distribution, shape, and acid phosphatase activity
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Kim IT, Choi JB
- KMID: 1043978
- Korean J Ophthalmol.
- 1998 Dec;12(2):85-91.
- doi: 10.3341/kjo.1998.12.2.85
The distribution and shape of melanosomes of the retinal pigment epithelium (RPE), and acid phosphatase activity in melanosomes were studied in rabbits. The rabbit eyes were observed using electron microscopy... -
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- Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
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Ciechanover A, Kwon YT
- KMID: 2155412
- Exp Mol Med.
- 2015 Mar;47(3):e147.
- doi: 10.1038/emm.2014.117
Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the... -
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- Biochemical Characteristics of a Korean Patient with Mucolipidosis III (Pseudo-Hurler Polydystrophy)
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Song J, Lee DS, Cho HI, Kim JQ, Cho TJ
- KMID: 1130045
- J Korean Med Sci.
- 2003 Oct;18(5):722-726.
- doi: 10.3346/jkms.2003.18.5.722
We performed a biochemical study on the patient with mucolipidosis III (ML-III, pseudo-Hurler polydystrophy) in Korea. Confluent fibroblasts from the patient and from normal controls were cultured for 4, 12,... -
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