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A model for the reaction mechanism of the transglutaminase 3 enzyme

Ahvazi B, Steinert P

  • KMID: 1109310
  • Exp Mol Med.
  • 2003 Aug;35(4):228-242.
Transglutaminase enzymes (TGases) catalyze the calcium dependent formation of an isopeptide bond between protein-bound glutamine and lysine substrates. Previously we have shown that activated TGase 3 acquires two additional calcium...
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Integrative epigenomic and genomic analysis of malignant pheochromocytoma

Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C

Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to...
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