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Effects of Oxidative DNA Damage and Genetic Polymorphism of the Glutathion Peroxidase 1 (GPX1) and 8-Oxoguanine Glycosylase 1 (hOGG1) on Lung Cancer

Lee CH, Lee KY, Choe KH, Hong YC, Noh SI, Eom SY, Ko YJ, Zhang YW, Yim DH, Kang JW, Kim H, Kim YD

  • KMID: 792399
  • J Prev Med Public Health.
  • 2006 Mar;39(2):130-134.
OBJECTIVES: Oxidative DNA damage is a known risk factor of lung cancer. The glutathione peroxidase (GPX) antioxidant enzyme that reduces hydrogen peroxide and lipid peroxides plays a significant role...
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Effects of Oxidative DNA Damage Induced by Polycyclic Aromatic Hydrocarbons and Genetic Polymorphism of the Paraoxonase-1 (PON1) Gene on Lung Cancer

Lee CH, Lee KY, Choe KH, Hong YC, Kim YD, Kang JW, Kim H

  • KMID: 1083325
  • J Prev Med Public Health.
  • 2005 Aug;38(3):345-350.
OBJECTIVE: Polycyclic aromatic hydrocarbons (PAHs), which are risk factors for lung cancer, have been reported to induce oxidative DNA damage. The paraoxonase (PON) plays a significant role in the detoxification...
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