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A New Reporter Vector System Based on Flow-Cytometry to Detect Promoter Activity

Jung S, Choi JH, Hong C, Lee H, Park YK, Shin JH, Park JW, Park SH

In this study, we report the development of a new dual reporter vector system for the analysis of promoter activity. This system employs green fluorescence emitting protein, EGFP, as a...
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Distribution of Adenoviral Vector in Brain after Intravenous Administration

Jin JY, Moon CI, Moon CI, Kang WS, Jeong DC

The delivery of transgenes to the central nervous system (CNS) can be a valuable tool to treat CNS diseases. Various systems for the delivery to the CNS have been developed;...
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Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells

Park KS, Wiederkehr A, Wollheim C

Mitochondrial dynamics and distribution is critical for their role in bioenergetics and cell survival. We investigated the consequence of altered fission/fusion on mitochondrial function and motility in INS-1E rat clonal...
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Monitoring transfected cells without selection agents by using the dual-cassette expression EGFP vectors

Kang SG, Lee EK, Schaus S, Henderson

  • KMID: 938883
  • Exp Mol Med.
  • 2001 Sep;33(3):174-178.
Conventional methods of selecting gene transfected cells by toxic agents may yield ambiguous results. It is difficult to determine whether cell death is due to selection agents or gene transfection,...
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Post-mortem re-cloning of a transgenic red fluorescent protein dog

Hong SG, Koo OJ, Oh HJ, Park JE, Kim M, Kim GA, Park EJ, Jang G, Lee BC

Recently, the world's first transgenic dogs were produced by somatic cell nuclear transfer. However, cellular senescence is a major limiting factor for producing more advanced transgenic dogs. To overcome this...
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