- Retroviral-mediated IL-12 gene therapy for advanced murine tumors
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Kim SH, An CS, Tahara H, Park CH, Lotze MT, Robbins PD, Kim SY
- KMID: 2128626
- Exp Mol Med.
- 1997 Mar;29(1):53-58.
Interleukin 12 (IL-12), a heterodimeric cytokine, promotes an effective antitumor response against tumors of various histological types when delivered systemically as a protein or locally by gene transfer. We investigated... -
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- Production of IL-12 from gene modified human dermal fibroblasts: A preclinical study for IL-12 cancer gene therapy
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Park CH, Kang WK, Oh MS, Kim WS, Yang JH, Lotze MT, Kim SY, Park K, Park CH
- KMID: 2128628
- Exp Mol Med.
- 1997 Mar;29(1):65-69.
Cytokine has been used as an immune stimulator and administered to patients for a treatment of cancer. Interleukin-12 (IL-12) is a potent cytokine which acts through a variety of functions... -
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