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Prediction of the Duration to Next Admission for an Acute Affective Episode in Patients with Bipolar I Disorder

Chen PH, Shih CM, Chang CK, Lin CP, Chang YH, Lee HC, Loh EW

Objective: Predicting disease relapse and early intervention could reduce symptom severity. We attempted to identify potential indicators that predict the duration to next admission for an acute affective episode in...
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Effectiveness of N-acetylcysteine in Treating Clinical Symptoms of Substance Abuse and Dependence: A Meta-analysis of Randomized Controlled Trials

Chang CT, Hsieh PJ, Lee HC, Lo CH, Tam KW, Loh EW

Objective: Treatment with N-acetylcysteine (NAC) is believed to reduce the clinical symptoms among individuals with substance abuse or dependence. We conducted a meta-analysis of randomized controlled trials to evaluate the...
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Association of the PPAR-gamma Gene with Altered Glucose Levels and Psychosis Profile in Schizophrenia Patients Exposed to Antipsychotics

Liu YR, Hu TM, Lan TH, Chiu HJ, Chang YH, Chen SF, Yu YH, Chen CC, Loh EW

OBJECTIVE: Metabolic abnormalities, e.g., diabetes, are common among schizophrenia patients. Peroxisome proliferator activated receptor-gamma (PPAR-gamma) regulates glucose/lipid metabolisms, and schizophrenia like syndrome may be induced by actions involving retinoid X...
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