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Mutation analysis of p31(comet) gene, a negative regulator of Mad2, in human hepatocellular carcinoma

Yun MY, Kim SB, Park S, Han CJ, Han YH, Yoon SH, Kim SH, Kim CM, Choi DW, Cho MH, Park GH, Lee KH

  • KMID: 756074
  • Exp Mol Med.
  • 2007 Aug;39(4):508-513.
Failure of mitotic checkpoint machinery leads to the chromosomal missegregation and nuclear endoreduplication, thereby driving the emergence of aneuploidy and tetraploidy population. Although abnormal nuclear ploidy and the resulting impairment...
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Hepatitis C virus and hepatocarcinogenesis

Jeong SW, Jang JY, Chung RT

Hepatitis C virus (HCV) is an RNA virus that is unable to integrate into the host genome. However, its proteins interact with various host proteins and induce host responses. The...
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Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells

Jeon YJ, Kim YS

BACKGROUND/AIMS: Hypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. METHODS: Huh7 cells were...
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