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Hypermethylation of the RUNX3 gene in hepatocellular carcinoma

Park WS, Cho YG, Kim CJ, Song JH, Lee YS, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY

  • KMID: 1093462
  • Exp Mol Med.
  • 2005 Aug;37(4):276-281.
Methylation events play a critical role in various cellular processes including regulation of gene transcription and proliferation. Recently, RUNX3 gene, one of TGF-beta-Smads signaling transduction pathway genes, showed strong tumor-suppressor...
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Genetic and expression analysis of the KCNRG gene in hepatocellular carcinomas

Cho YG, Kim CJ, Song JH, Rhie DJ, Park YK, Kim SY, Nam SW, Yoo NJ, Lee JY, Park WS

  • KMID: 1094150
  • Exp Mol Med.
  • 2006 Jun;38(3):247-255.
The potassium channels are ubiquitous multisubunit membrane proteins, and potassium-dependent alterations in the membrane potential play an important role in the proliferation of many types of cells. This study analyzed...
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