- NADPH Oxidase 1 and NADPH Oxidase 4 Have Opposite Prognostic Effects for Patients with Hepatocellular Carcinoma after Hepatectomy
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Ha SY, Paik YH, Yang JW, Lee MJ, Bae H, Park CK
- KMID: 2412082
- Gut Liver.
- 2016 Sep;10(5):826-835.
- doi: 10.5009/gnl15543
BACKGROUND/AIMS: Nicotinamide adenine dinucleotide phosphate oxidase (NOX)-mediated reactive oxygen species contribute to various liver diseases, including hepatocellular carcinoma (HCC). Uncertainties remain regarding the prognostic relevance of NOX1 and NOX4 protein... -
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- Regulation of cell growth by fatty acid-CoA ligase 4 in human hepatocellular carcinoma cells
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Sung YK, Park MK, Hong SH, Hwang SY, Kwack MH, Kim JC, Kim MK
- KMID: 756070
- Exp Mol Med.
- 2007 Aug;39(4):477-482.
Fatty acid-CoA ligase 4 (FACL4) is a central enzyme controlling the unesterified free arachidonic acid (AA) level in cells and the free AA is known to induce apoptosis. We have... -
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- A novel prognostic factor for hepatocellular carcinoma: protein disulfide isomerase
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Yu SJ, Won JK, Ryu HS, Choi WM, Cho H, Cho EJ, Lee JH, Kim YJ, Suh KS, Jang JJ, Kim CY, Lee HS, Yoon JH, Cho KH
- KMID: 1794622
- Korean J Intern Med.
- 2014 Sep;29(5):580-587.
- doi: 10.3904/kjim.2014.29.5.580
BACKGROUND/AIMS: Protein disulfide isomerase (PDI) has been implicated in the survival and progression of some cancer cells, by compensating for endoplasmic reticulum stress by upregulating the protein-folding capacity. However, its... -
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