- Anticarcinogenic Effect of Red Ginseng on the Development of Liver Cancer Induced by Diethylnitrosamine in Rats
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Wu XG, Zhu DH, Li X
- KMID: 1721176
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S61-S65.
- doi: 10.3346/jkms.2001.16.S.S61
Anticarcinogenic effect of red ginseng (Panax ginseng C.A. Meyer cultivated in JiLin, China) on the development of liver cancer induced by diethylnitrosamine (DEN) in rats was studied, especially in preventive... -
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- Surface Properties of Cell Membrane in Early Stage of Transformed Cell -I. Early Detection of Transformed Cell by Concanavalin A; II. Properties of Plasma Membrane of Transformed Rat Liver Cell Induced by 3'-Me DAB
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Kim YS, Cho MY
- KMID: 1729534
- Yonsei Med J.
- 1985 Dec;26(2):167-174.
- doi: 10.3349/ymj.1985.26.2.167
The present study was designed in order to investigate the lectin induced cytoagglutination properties of normal and transformed cells and surface alterations in the early stage of the transformed cells... -
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- Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis
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Ha WS, Kim CK, Song SH, Kang CB
- KMID: 1103507
- J Vet Sci.
- 2001 Apr;2(1):53-58.
With the aim of establishing bio-indices for the development of multistep hepatotumorigenesis, rats were fed water containing 0.01% diethylnitrosamine (DEN) ad libitum for 13 weeks. This treatment with DEN only... -
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- Impact of Energy and Access Methods on Extrahepatic Tumor Spreading and the Ablation Zone: An Ex vivo Experiment Using a Subcapsular Tumor Model
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Kim JS, Ko Y, Kwon H, Kim M, Lee JK
- KMID: 2440481
- Korean J Radiol.
- 2019 Apr;20(4):580-588.
- doi: 10.3348/kjr.2018.0564
OBJECTIVE: To evaluate the impact of energy and access methods on extrahepatic tumor spreading and the ablation zone in an ex vivo subcapsular tumor mimic model with a risk of... -
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- Transferrin receptor expression of the hyperplastic lesions of hepatocyte in experimental hepatocarcinogenesis
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Park CI, Park YN, Jung WH
- KMID: 1054342
- J Korean Med Sci.
- 1995 Jun;10(3):183-188.
- doi: 10.3346/jkms.1995.10.3.183
Transferrin receptor (TR) performs the major function of binding and internalizing its specific iron-loaded ligand, transferrin, and its expression is closely linked to the proliferation status of the cell. This... -
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- Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat
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Jang JJ, Cho KJ, Lee YS, Bae JH
- KMID: 1421512
- J Korean Med Sci.
- 1991 Mar;6(1):31-36.
- doi: 10.3346/jkms.1991.6.1.31
The modifying potential of capsaicin (CAP) on lesion development was examined in a rat multiorgan carcinogenesis model. Groups 1 and 2 were treated sequentially with diethylnitrosamine (DEN) (100 mg/kg, ip,... -
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- Cancer Chemoprevention by Ginseng in Mouse Liver and Other Organs
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Nishino H, Tokuda H, Ii T, Takemura M, Kuchide M, Kanazawa M, Mou XY, Bu P, Takayasu J, Onozuka M, Masuda M, Satomi Y, Konoshima , Kishi N, Baba M, Okada Y, Okuyama T
- KMID: 1721177
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S66-S69.
- doi: 10.3346/jkms.2001.16.S.S66
Oral administration of red ginseng extracts (1% in diet for 40 weeks) resulted in the significant suppression of spontaneous liver tumor formation in C3H/He male mice. Average number of tumors... -
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- Nucleolus contains signal molecules that constitute membrane-nucleolus linked pathway
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Jeong JS, Kim IH, Lee HJ, Choi YC
- KMID: 755010
- Exp Mol Med.
- 1998 Dec;30(4):205-213.
Since there have been very few studies on nucleolar signaling, an attempt was made to establish nucleolar signal pathways which link the cell membrane to the nucleolus for the transfer... -
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- Factors Influencing the Pathogenicity of Entamoeba Histolytica
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Soh CT
- KMID: 693106
- Yonsei Med J.
- 1988 Mar;29(1):1-10.
- doi: 10.3349/ymj.1988.29.1.1
In summarizing the results of the experimental studies up to the present, it is conjectured that the pathogenicity of Entamoeba histolytica or establishment of amoebiasis is not unique but differs... -
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- Expression of ErbB Receptor Proteins and TGF-alpha during Diethylnitrosamine-induced Hepatocarcinogenesis in the Rat Liver
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Lee TY, Kim KT, Han SY
- KMID: 760707
- Korean J Hepatol.
- 2007 Mar;13(1):70-80.
BACKGROUND/AIMS: ErbB receptor proteins are transmembrane tyrosine kinase receptors; when they are activated by interaction with ligands, they generate diverse cellular responses, especially during lesion development and progression to... -
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- Purification of r-Glutamyltranspeptidase from Rat Primary Hepatoma Tissue and Preparation of a Tumor Associated Antigen
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Oh SH, Woo K
- KMID: 693110
- Yonsei Med J.
- 1988 Mar;29(1):37-48.
- doi: 10.3349/ymj.1988.29.1.37
r-Glutamyltranspeptidase (r-GT) from a rat hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene (3'-Me DAB) was purified 833 fold. The purified enzyme had a specific activity of 15.0 U/mg protein with an overall yield... -
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- FDG-PET for Evaluating the Antitumor Effect of Intraarterial 3-Bromopyruvate Administration in a Rabbit VX2 Liver Tumor Model
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Park HS, Chung JW, Jae HJ, Kim YI, Son KR, Lee MJ, Park JH, Kang WJ, Yoon JH, Chung H, Lee K
- KMID: 1779437
- Korean J Radiol.
- 2007 Jun;8(3):216-224.
- doi: 10.3348/kjr.2007.8.3.216
OBJECTIVE: We wanted to investigate the feasibility of using FDG-PET for evaluating the antitumor effect of intraarterial administration of a hexokinase II inhibitor, 3-bromopyruvate (3-BrPA), in a rabbit VX2 liver... -
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- Effects of Arsenic Trioxide on Radiofrequency Ablation of VX2 Liver Tumor: Intraarterial versus Intravenous Administration
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Seong NJ, Yoon CJ, Kang SG, Chung JW, Kim HC, Park JH
- KMID: 1245384
- Korean J Radiol.
- 2012 Apr;13(2):195-201.
- doi: 10.3348/kjr.2012.13.2.195
OBJECTIVE: Arsenic trioxide (As2O3) can be used as a possible pharmaceutical alternative that augments radiofrequency (RF) ablation by reducing tumor blood flow. The aim of this study was to assess... -
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- Characterization of Tumor Specific Antigens on the Plasma Membrane Surface of Rat Hepatomas lnduced by 3'-Me DAB and ldentification of the Common Tumor Specific Antigens from Rat Hepatomas lnduced by Different Chemical Hepatocarcinogens
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Kim YS, Hahm KS, Kim KS, Lee NJ
- KMID: 693108
- Yonsei Med J.
- 1988 Mar;29(1):17-28.
- doi: 10.3349/ymj.1988.29.1.17
Three different chemical carcinogens, 2-acetylaminofluorene (AAF), diethylnitrosamine(DENA), and 3'-methyl-4dimethylaminoazobenzene (3'-Me DAB) were used to induce hepatomas in rats. Plasma membrane surface proteins of normal rat liver cells and rat hepatomas... -
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- A Study of the Regulation of the Glucose Transporter in the Plasma Membranes of Hepatoma Cells Induced by 3'-Me DAB
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Ahn YH, Chai KJ, Kim SN, Kim YS
- KMID: 693085
- Yonsei Med J.
- 1987 Sep;28(3):192-198.
- doi: 10.3349/ymj.1987.28.3.192
5'-nucelotidase and glucose-6-phosphatase are liver plasma and microsomal membranes markers and their respective activities were determined. In the liver homogenate, the activities of 5'-nucleotidase were 0.58 +/- 0.08 and 0.29... -
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- Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride
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Qin G, Ning Y, Su J, Shinozuka , Lotlikar P
- KMID: 755007
- Exp Mol Med.
- 1998 Dec;30(4):186-191.
The effect of carbon tetrachloride (CCl4) on aflatoxin B1 (AFB1)-induced enzyme altered hepatic foci has been examined in young male Fischer rats given AIN-76A diet. A single i.p. dose of... -
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- A study on the regulation of translocation of glucose transporters during hepatocarcinogenesis induced by 3'-Me DAB
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Kim YS, Paik EM, Lee MS, Kim KS, Chai KJ, Ahn YH
- KMID: 1729578
- Yonsei Med J.
- 1990 Dec;31(4):315-324.
- doi: 10.3349/ymj.1990.31.4.315
The mechanism of glucose transported (GT) expression on the plasma membranes of hepatoma cells in rats induced by 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB) was studied. Cytochalasin B binding to plasma membrane fractions from... -
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- Small Animal PET Imaging with [124I]FIAU for Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression in a Hepatoma Model
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Chae MJ, Lee TS, Kim JY, Woo GS, Jumg WS, Chun KS, Kim JH, Lee JS, Ryu JS, Cheon GJ, Choi CW, Lim SM
- KMID: 2313046
- Nucl Med Mol Imaging.
- 2008 Jun;42(3):235-234.
PURPOSE: The HSV1-tk gene has been extensively studied as a type of reporter gene. In hepatocellular carcinoma (HCC), only a small proportion of patients are eligible for surgical resection and... -
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- Expressions of c-fos and c-myc genes during 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB)-induced rat hepatocarcinoma
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Chai KJ, Kim JS, Lee HK
- KMID: 1120235
- Yonsei Med J.
- 1992 Sep;33(3):240-248.
- doi: 10.3349/ymj.1992.33.3.240
We investigated the expression of the growth-related nuclear proto-oncogenes, c-fos and c-myc, in early preneoplastic regions and tumor nodules of 3'-MeDAB induced rat hepatocarcinoma. To amplify the levels of these... -
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- The effect of deferoxamine on the preneoplastic lesions in the chemically induced hepatocarcinogenesis
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Park YN, Jung WH, Park C
- KMID: 1125976
- Yonsei Med J.
- 1994 Dec;35(4):388-395.
- doi: 10.3349/ymj.1994.35.4.388
Iron is essential for the growth of all living cells. One of the most important intracellular roles of iron is the activation of ribonucleotide reductase, which is indispensible to the... -
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