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A Study of Hepatic Injury Induced by Endotoxin in Rats

Lee DW, Kim CS, Lee YB, Kim DS

To study the mechanism of endotoxin-induced hepatocellular injury in rats, a single dose of endotoxin, 15mg/kg, was injected intraperitoneally with or without dexamethasone pretreatment. Studies included light microscopic, histochemical, and...
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Glucocorticoid-induced laminitis with hepatopathy in a Thoroughbred filly

Ryu SH, Kim BS, Lee CW, Yoon J, Lee YL

  • KMID: 1099844
  • J Vet Sci.
  • 2004 Sep;5(3):271-274.
A 3-year-old Thoroughbred filly was referred to the Equine Hospital, Korea Racing Association for evaluation of hematuria, inappetite, weight loss and depression. From 25 days prior to admission, the horse...
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Temozolomide Chemotherapy in Patients with Recurrent Malignant Gliomas

Yang SH, Kim MK, Lee TK, Lee KS, Jeun SS, Park CK, Kang JK, Kim MC, Hong YK

Numerous studies have demonstrated the clinical activity of temozolomide, a second-generation alkylating agent, against malignant brain tumors, however, its activity has not been reported in an Asian population. This study...
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Hepatitis B and C Virus Infection and Liver Dysfunction in Patients Receiving Chemotherapy

Kwon CI, Lee JH, Choi KH, Ko KH, Hong SP, Hwang SG, Park PW, Oh D, Rim KS, Kim S

  • KMID: 782802
  • Korean J Gastroenterol.
  • 2006 Dec;48(6):408-414.
BACKGROUND/AIMS: Liver dysfunction and reactivation of hepatitis virus are well-described complications in cancer patients who receive cytotoxic chemotherapy and may result in varying degrees of liver damage. However, there...
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The effect of aflatoxin B1 on the expression of early response genes and transforming growth factor-alpha in CCl4 induced rat liver injury

Hong SW, Park C

Aflatoxin B1 (AFB1), a fungal toxin produced by Aspergillus flavus, is known to be a possible hepatocarcinogen. But the molecular biologic changes which may occur following exposure to...
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Expression of G1 Cell Cycle Regulators in Rat Liver upon Repeated Exposure to Thioacetamide

Kim KT, Han SY, Jeong JS

  • KMID: 760708
  • Korean J Hepatol.
  • 2007 Mar;13(1):81-90.
BACKGROUND/AIMS: Eukaryotic cell cycle is regulated by signal transduction pathways mediated by complexes of cyclin dependent kinases (CDKs) and their partner cyclins, or by interaction with CDK inhibitors. Thioacetamide...
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