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Effect of metal ions on the stability of metallothionein in the degradation by cellular fractions in vitro

Hahn SH, Yoo OJ, Gahl WA

  • KMID: 755115
  • Exp Mol Med.
  • 2001 Mar;33(1):32-36.
Metallothioneins (MT), small molecular weight metal binding proteins are known to play an important protective role against heavy metal toxicity, either as antioxidants or pre-oxidants. However, the mode of metabolic...
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The Metabolism and Liver Toxicity of N,N-dimethylformamide in the Isolated Perfused Rat Liver

Koh SB, Cha BS, Park JK, Chang SH, Chang SJ

N,N-dimethylformamide (DMF) is metabolized by the microsomal cytochrome p-450 into mainly N-hydroxymethyl- N-methylformamide (HMMF), which further breaks down to N-methyformamide (NMF). However, the detailed mechanism of its toxicity remains unclear....
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The Effect of Endotoxin on the Expression of Tissue Factor in the CCl4-treated Rat Liver

Cho M, Seo SB, Heo J, Kim GH, Kang DH, Song GA, Yang US

  • KMID: 772537
  • Korean J Gastroenterol.
  • 2003 Aug;42(2):149-155.
BACKGROUND/AIMS: Endotoxemia is known to cause hepatic microcirculation disturbance and hepatic injury through blood coagulation and thromobosis in the cirrhotic patients. This study was to investigate the effect of...
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