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Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice

Yi J, Xia W, Wu J, Yuan L, Wu J, Tu D, Fang J, Tan Z

Betulinic acid (BA), a pentacyclic lupane-type triterpene, has a wide range of bioactivities. The main objective of this work was to evaluate the hepatoprotective activity of BA and the potential...
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Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice

Abouelella AM, Shahein YE, Tawfik SS, Zahran AM

Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice....
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Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver

Kweon S, Kim Y, Choi H

  • KMID: 1093609
  • Exp Mol Med.
  • 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet...
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Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease

Illnait J, Rodriguez , Mendoza S, Fernandez , Mas R, Miranda M, Pinera J, Fernandez , Mesa M, Fernandez , Carbajal D, Gamez R

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and...
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Physical Activity- and Alcohol-dependent Association Between Air Pollution Exposure and Elevated Liver Enzyme Levels: An Elderly Panel Study

Kim KN, Lee H, Kim JH, Jung K, Lim YH, Hong YC

OBJECTIVES: The deleterious effects of air pollution on various health outcomes have been demonstrated. However, few studies have examined the effects of air pollution on liver enzyme levels. METHODS: Blood samples...
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Expression of G1 Cell Cycle Regulators in Rat Liver upon Repeated Exposure to Thioacetamide

Kim KT, Han SY, Jeong JS

  • KMID: 760708
  • Korean J Hepatol.
  • 2007 Mar;13(1):81-90.
BACKGROUND/AIMS: Eukaryotic cell cycle is regulated by signal transduction pathways mediated by complexes of cyclin dependent kinases (CDKs) and their partner cyclins, or by interaction with CDK inhibitors. Thioacetamide...
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