- JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis
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Xie L, Chen H, Zhang L, Ma Y, Zhou Y, Yang YY, Liu C, Wang YL, Yan YJ, Ding J, Teng X, Yang Q, Liu XP, Wu J
- KMID: 2554427
- Clin Mol Hepatol.
- 2024 Apr;30(2):206-224.
- doi: 10.3350/cmh.2023.0506
Background/Aims: Cholestatic liver diseases including primary biliary cholangitis (PBC) are associated with active hepatic fibrogenesis, which ultimately progresses to cirrhosis. Activated hepatic stellate cells (HSCs) are the main fibrogenic effectors... -
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