- IL-13 R110Q, a Naturally Occurring IL-13 Polymorphism, Confers Enhanced Functional Activity in Cultured Human Bronchial Smooth Muscle Cells
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He YF, Hua L, Bao YX, Liu QH, Chu Y, Fang DZ
- KMID: 2260281
- Allergy Asthma Immunol Res.
- 2013 Nov;5(6):377-382.
- doi: 10.4168/aair.2013.5.6.377
PURPOSE: Interleukin (IL)-13, a Th2-type cytokine, plays a pivotal role in the pathogenesis of asthma through its direct effects on airway smooth muscles. A naturally occurring IL-13 polymorphism, R110Q, is... -
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- IL-17A exacerbates diabetic retinopathy by impairing Müller cell function via Act1 signaling
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Qiu AW, Bian Z, Mao PA, Liu QH
- KMID: 2367556
- Exp Mol Med.
- 2016 Dec;48(12):e280.
- doi: 10.1038/emm.2016.117
Diabetic retinopathy (DR), one of the most serious complications of diabetes, has been associated with inflammatory processes. We have recently reported that interleukin (IL)-17A, a proinflammatory cytokine, is increased in... -
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