- Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase
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Han SJ, Kim JI, Lipschutz JH, Park KM
- KMID: 2521485
- Korean J Physiol Pharmacol.
- 2021 Nov;25(6):593-601.
- doi: 10.4196/kjpp.2021.25.6.593
Primary cilia on kidney tubular cells play crucial roles in maintaining structure and physiological function. Emerging evidence indicates that the absence of primary cilia, and their length, are associated with... -
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- High water intake induces primary cilium elongation in renal tubular cells
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Kong MJ, Han SJ, Seu SY, Han KH, Lipschutz JH, Park KM
- KMID: 2557314
- Kidney Res Clin Pract.
- 2024 May;43(3):313-325.
- doi: 10.23876/j.krcp.23.087
Background: The primary cilium protrudes from the cell surface and functions as a mechanosensor. Recently, we found that water intake restriction shortens the primary cilia of renal tubular cells, and... -
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- Shortening of primary cilia length is associated with urine concentration in the kidneys
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Kong MJ, Han SJ, Seu SY, Han KH, Lipschutz JH, Park KM
- KMID: 2543786
- Kidney Res Clin Pract.
- 2023 May;42(3):312-324.
- doi: 10.23876/j.krcp.22.274
Background: The primary cilium, a microtubule-based cellular organelle present in certain kidney cells, functions as a mechano-sensor to monitor fluid flow in addition to various other biological functions. In kidneys,... -
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