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Altered Vascular Response to the K+induced Vasorelaxation in Aortic Smooth Muscle of Renal Hypertensive Rats

Jun JY, Yeum CH, Yoon PJ, Liee JH, Choi HH, Park YW, Kim JH

BACKGROUND: An increase of the extracellular K+concentrations up to about 8 mM in the isolated vessels causes relaxation in pre-contracted state. In order to elucidate the mechanisms of K+induced relaxation...
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Role of Tyrosine Kinases in 5-HT-Induced Vascular Contraction in Two-Kidney, One Clip Hypertensive Rats

Yeum CH, Kim JS, Jun JY, Kim JH, Liee JH, Yoon PJ

  • KMID: 2254581
  • Korean J Nephrol.
  • 2000 Jan;19(1):40-48.
Tyrosine kinases have been implicated in vascular smooth muscle cell proliferation and contraction. The involvement of tyrosine kinases in 5-hydroxytryptamine (5-HT)-induced contractile response of the isolated aorta was examined in...
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Pressor Responses to Intracerebroventricular Infusion of Hypertonic NaCl in Renal Hypertensive Rats

Yeum CH, Park CH, Jun JY, Kim JH, Liee JH, Hong SP, Yoon PJ

BACKGROUND: The sodium concentration in the central nervous system may play an important role in cardiovascular function and body fluid regulation. The purpose of this investigation was to examine the...
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Effects of Endogenous Nitric Oxide Synthesis Inhibition on the Depressor Response to Intracerebroventricular Calcium

Yeum CH, Moon IK, Jun JY, Liee JH, Cheon KB, Yoon PJ

BACKGROUND: Aside from its well known peripheral antihypertensive effects, calcium also lowers blood pressure, when administered into the cerebral ventricle. The present study was aimed to determine whether the central...
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Cardiovascular Effects of Nifedipine and Bay K 8644 in Hypertensive Rats

Choi TM, Kim JS, Moon SH, Oh HK, Liee JH, Jun JY, Yeum CH, Yoon PJ, Hong SP

BACKGROUND: Calcium plays a key role in vascular contraction and regulates receptor sensitivity to certain neurotransmitters. Calcium channel blockers are useful in the treatment of both clinical and experimental hypertension....
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