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Post-Acute Care as a Key Component in a Healthcare System for Older Adults

Wang YC, Chou MY, Liang CK, Peng LN, Chen LK, Loh CH

Older adults often experience functional decline following acute medical care. This functional decline may lead to permanent disability, which will increase the burden on the medical and long-term care systems,...
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Lack of Association between Pre-Operative Insulin-Like Growth Factor-1 and the Risk of Post-Operative Delirium in Elderly Chinese Patients

Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chu CL, Chou PH

OBJECTIVE: Postoperative delirium (POD) is a highly prevalent complex neuropsychiatric syndrome in elderly patients. However, its pathophysiology is currently unknown. Early detection and prevention of POD is important; therefore, the...
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Lipopolysaccharide-induced Autophagy Increases SOX2-positive Astrocytes While Decreasing Neuronal Differentiation in the Adult Hippocampus

Liu WC, Wu CW, Fu MH, Tain YL, Liang CK, Chen IC, Hung CY, Lee YC, Wu KL

  • KMID: 2535062
  • Exp Neurobiol.
  • 2022 Oct;31(5):307-323.
  • doi: 10.5607/en22005
Inflammation alters the neural stem cell (NSC) lineage from neuronal to astrogliogenesis. However, the underlying mechanism is elusive. Autophagy contributes to the decline in adult hippocampal neurogenesis under E. coli...
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