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The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model

Muz MH, Deveci F, Bulut Y, Ilhan N, Yekeler H, Turgut T

  • KMID: 1111403
  • Exp Mol Med.
  • 2006 Apr;38(2):109-118.
Airway structural changes that occur in patients with asthma in response to persistent inflammation are termed airway remodeling. The cysteinyl leukotrienes (LTC4, D4 and E4) are known to play important...
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Leukotriene-related Gene Polymorphisms in Patients with Aspirin-intolerant Urticaria and Aspirin-intolerant Asthma: Differing Contributions of ALOX5 Polymorphism in Korean Population

Kim SH, Choi JH, Holloway J, Suh CH, Nahm DH, Ha EH, Park CS, Park HS

The pathogenesis of aspirin (acetylsalicylic acid, ASA)-intolerant urticaria (AIU) is still poorly understood but it has recently been suggested that it is associated with the overproduction of leukotriene (LT). This...
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