- Leukostasis by hyperleukocytic childhood acute leukemia: pathophysiology, clinical presentation, and emergency care
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Nam KL, Baek GY, Jeon IS
- KMID: 2469716
- Pediatr Emerg Med J.
- 2019 Dec;6(2):35-41.
- doi: 10.22470/pemj.2019.00150
Hyperleukocytosis (HL), defined by a peripheral white blood cell (WBC) count exceeding 100,000/mm³, is occasionally observed in childhood acute leukemia. The increased viscosity in the micro-circulation by HL and the... -
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- Leukapheresis with high dose hydroxyurea in the management of lower leg artery obstruction in Chronic Myelogenous Leukemia
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Lim CS, Lee SO, Kwak JY, Yim CY
- KMID: 2306355
- Korean J Med.
- 1998 Nov;55(5):960-964.
There was no specific criteria of white cell count to determine the therapy of hyperleukocytosis in chronic myelogenous leukemia (CML). Therapeutic leukapheresis usually indicated in acute myelogenous leukemia with over... -
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- A Clinical Characteristics and Prognosis in Children of Acute Lymphoblastic Leukemia with Hyperleukocytosis
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Park JA, Park SS, Lim YT
- KMID: 2049206
- Clin Pediatr Hematol Oncol.
- 2006 Apr;13(1):1-8.
PURPOSE: Hyperleukocytosis combined with acute lymphoblastic leukemia (ALL) is associated with early morbidity and mortality because leukostasis interferes with the blood flow by leukocytes within the microcirculation and can result... -
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- Therapeutic Leukapheresis for Acute Lymphoblastic Leukemia with Severe Hyperleukocytosis in a Six-Week-Old Infant (4.7 kg)
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Byun JY, Shin KM, Won SC, Lyu CJ, Lim HS, Kim HO
- KMID: 1917300
- Korean J Pediatr Hematol Oncol.
- 2002 Oct;9(2):250-254.
We report a 4.7 kg infant who received a therapeutic leukapheresis as an immediate treatment for acute lymphoblastic leukemia with severe hyperleukocytosis. By decreasing the number of circulating white... -
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- Clinical Effects and Safety of Therapeutic Leukapheresis in Hyperleukocytosis
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Lee SN, Kong JH, Eom HS, Lee H, Park HJ, Sohn JY, Kong SY
- KMID: 2029269
- Korean J Blood Transfus.
- 2014 Aug;25(2):132-140.
- doi: 10.0000/kjbt.2014.25.2.132
BACKGROUND: Therapeutic leukapheresis is the cytoreduction procedure performed before chemotherapy in patients with hyperleukocytosis for prevention of complication. However, there have been clinical concerns about bleeding tendency due to anticoagulant... -
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- A Case of acute respiratory distress syndrome induced by all-trans-retinoic acid
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Kim C, Ko WK, Kwon SH, Kang SM, Kim CN, Yang DG, Kim SK, Chang J, Kim SK, Lee WY, Yang WI
- KMID: 2160258
- Tuberc Respir Dis.
- 2000 Jul;49(1):93-98.
- doi: 10.4046/trd.2000.49.1.93
Acute respiratory distress syndrome (ARDS) has been reported to be associated with a variety of medical and surgical conditions, including All-trans-retinoic acid (ATTA). ATRA is very efficaceous drug to acute... -
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- Evaluation of therapeutic leukapheresis in hyperleukocytic leukemias
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Lee YW, Jeong GY, Koo HH, Lee HG, Kim DW
- KMID: 2069262
- Korean J Blood Transfus.
- 1998 Dec;9(2):219-226.
BACKGROUND: Leukemia with hyperleukocytosis is risk factor for early mortality and morbidity. Therepeutic leukapheresis has been recognized as the choice of treatment modality to prevent leukostatic complications by selective removal... -
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- IL-17A exacerbates diabetic retinopathy by impairing Müller cell function via Act1 signaling
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Qiu AW, Bian Z, Mao PA, Liu QH
- KMID: 2367556
- Exp Mol Med.
- 2016 Dec;48(12):e280.
- doi: 10.1038/emm.2016.117
Diabetic retinopathy (DR), one of the most serious complications of diabetes, has been associated with inflammatory processes. We have recently reported that interleukin (IL)-17A, a proinflammatory cytokine, is increased in... -
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- Clinicohematologic Observations of Acute Leukemias with Hyperleukocytosis
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Lee YH, Hyun DW, Kim JG, Bae SK, Kwak DS, Sohn SK, Lee JT, Lee KB
- KMID: 2080494
- Korean J Med.
- 1997 Apr;52(4):534-541.
OBJECTIVES: It is well known that Acute Leukemic patients with Hyperleukocytosis (ALH, leukocyte count>or=100,000/micro L) have poor prognosis. This is indebted in fatal complications arising from cerebral and pulmonary leukostasis.... -
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