- Multi-drug resistance (MDR1) gene expression in de novo acute leukemia cells: correlations with CD surface markers and treatment outcome
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Jiang EZ, Chang YJ, Lee JW, Lee WK, Kim JS, Sohn SK, Lee KB, Suh JS
- KMID: 1038442
- J Korean Med Sci.
- 1998 Dec;13(6):617-622.
- doi: 10.3346/jkms.1998.13.6.617
One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the... -
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- TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells
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Lee JH, Park BJ, Park JH, Yang MH, Chi SG
- KMID: 755040
- Exp Mol Med.
- 1999 Sep;31(3):126-133.
To characterize the TGF-beta1 response of monocytic leukemia cells, we analyzed the effects of TGF-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic U937 cells. Treatment of cells with TGF-beta1 in... -
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