- Multi-drug resistance (MDR1) gene expression in de novo acute leukemia cells: correlations with CD surface markers and treatment outcome
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Jiang EZ, Chang YJ, Lee JW, Lee WK, Kim JS, Sohn SK, Lee KB, Suh JS
- KMID: 1038442
- J Korean Med Sci.
- 1998 Dec;13(6):617-622.
- doi: 10.3346/jkms.1998.13.6.617
One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the... -
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- Monitoring of WT-1 gene expression in peripheral blood of patients with acute leukemia by semiquantitative RT-PCR; possible marker for detection of minimal residual leukemia
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Kim SC, Yoo NC, Hahn JS, Lee S, Chong SY, Min YH, Ko YW
- KMID: 699953
- Yonsei Med J.
- 1997 Aug;38(4):212-219.
- doi: 10.3349/ymj.1997.38.4.212
The expression of the WT-1 gene which is found exclusively in human leukemic blasts frequently disappears from bone marrow of leukemia patients in complete remission (CR). Using semiquantitative RT-PCR, we... -
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