- Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo
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Kim J, Kim OS, Kim CS, Sohn E, Jo K, Kim JS
- KMID: 1120135
- Exp Mol Med.
- 2012 Feb;44(2):167-175.
- doi: 10.3858/emm.2012.44.2.012
The formation of advanced glycation end products (AGEs) has been considered to be a potential causative factor of injury to lens epithelial cells (LECs). Damage of LECs is believed to... -
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- Possible Role of Amyloid beta- (1-40) -BSA Conjugates in Transdifferentiation of Lens Epithelial Cells
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Lee KW, Seomun Y, Kim DH, Park SY, Joo CK
- KMID: 2428316
- Yonsei Med J.
- 2004 Apr;45(2):219-228.
We investigated whether amyloid beta (Abeta) aggregates have transforming growth factor beta- like cytokine activity and cause transdifferention of lens epithelial cells, leading to certain types of cataract. In order... -
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- Transdifferentiation of Cultured Bovine Lens Epithelial Cells into Myofibroblast-like Cells by Serum Modulation
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Kim JT, Lee EH, Chung KH, Kang IC, Lee DH, Joo CK
- KMID: 1734118
- Yonsei Med J.
- 2004 Jun;45(3):380-391.
- doi: 10.3349/ymj.2004.45.3.380
An after-cataract is caused by the proliferation of residual cells over the equator of the lens. These cells subsequently migrate to the posterior lens capsule, where they undergo aberrant differentiation... -
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