- Tamoxifen Induces Apoptosis of Leishmania major Promastigotes in Vitro
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Doroodgar , Delavari M, Doroodgar , Abbasi A, Taherian A, Doroodgar
- KMID: 2374011
- Korean J Parasitol.
- 2016 Feb;54(1):9-14.
- doi: 10.3347/kjp.2016.54.1.9
Tamoxifen is an antagonist of the estrogen receptor and currently used for the treatment of breast cancer. The current treatment of cutaneous leishmaniasis with pentavalent antimony compounds is not satisfactory.... -
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- Effects of combined therapy with thalidomide and glucantime on leishmaniasis induced by Leishmania major in BALB/c mice
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Solgi G, Kariminia , Abdi K, Darabi M, Ghareghozloo B
- KMID: 1091837
- Korean J Parasitol.
- 2006 Mar;44(1):55-61.
- doi: 10.3347/kjp.2006.44.1.55
For treating Leishmania major infection in BALB/c mice, we used thalidomide in conjunction with glucantime. Groups of mice were challenged with 5 x 10(3) metacyclic promastigotes of L. major subcutaneously.... -
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- In Vitro Infectivity Assessment by Drug Susceptibility Comparison of Recombinant Leishmania major Expressing Enhanced Green Fluorescent Protein or EGFP-Luciferase Fused Genes with Wild-Type Parasite
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Sadeghi S, Seyed N, Etemadzadeh MH, Abediankenari S, Rafati S, Taheri T
- KMID: 2381755
- Korean J Parasitol.
- 2015 Aug;53(4):385-394.
- doi: 10.3347/kjp.2015.53.4.385
Leishmaniasis is a worldwide uncontrolled parasitic disease due to the lack of effective drug and vaccine. To speed up effective drug development, we need powerful methods to rapidly assess drug... -
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- Anti-leishmanial Effects of Trinitroglycerin in BALB/C Mice Infected with Leishmania major via Nitric Oxide Pathway
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Nahrevanian H, Najafzadeh M, Hajihosseini R, Nazem H, Farahmand , Zamani Z
- KMID: 1720619
- Korean J Parasitol.
- 2009 Jun;47(2):109-115.
- doi: 10.3347/kjp.2009.47.2.109
This study investigated whether trinitroglycerine (TNG) as nitric oxide (NO) releasing agent had anti-leishmanial effects and mediated pathology in BALB/c mice infected with Leishmania major. Cutaneous leishmaniasis (CL), a zoonotic... -
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