- Leishmania tropica infection, in comparison to Leishmania major, induces lower delayed type hypersensitivity in BALB/c mice
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Mahmoudzadeh-Niknam H, Kiaei SS, Iravani D
- KMID: 1720533
- Korean J Parasitol.
- 2007 Jun;45(2):103-109.
- doi: 10.3347/kjp.2007.45.2.103
Leishmania tropica and L. major are etiologic agents of human cutaneous leishmaniasis. Delayed type hypersensitivity (DTH) is an immunologic response that has been frequently used as a correlate for protection... -
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- The Route of Leishmania tropica Infection Determines Disease Outcome and Protection against Leishmania major in BALB/c Mice
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Mahmoudzadeh-Niknam H, Khalili G, Abrishami , Najafy A, Khaze V
- KMID: 1501812
- Korean J Parasitol.
- 2013 Feb;51(1):69-74.
- doi: 10.3347/kjp.2013.51.1.69
Leishmania tropica is one of the causative agents of leishmaniasis in humans. Routes of infection have been reported to be an important variable for some species of Leishmania parasites. The... -
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- Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis
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Nemati S, Fazaeli A, Hajjaran H, Khamesipour A, Anbaran MF, Bozorgomid A, Zarei F
- KMID: 2389971
- Korean J Parasitol.
- 2017 Aug;55(4):367-374.
- doi: 10.3347/kjp.2017.55.4.367
Despite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the genetic characteristics of the causative agents. Applying both HSP70 PCR-RFLP and sequence... -
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- Purification and biochemical characterization of two novel antigens from Leishmania major promastigotes
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Zeinali M, Ardestani , Kariminia
- KMID: 1089950
- Korean J Parasitol.
- 2007 Dec;45(4):287-293.
- doi: 10.3347/kjp.2007.45.4.287
The identification and characterization of antigens that elicit human T cell responses is an important step toward understanding of Leishmania major infection and ultimately in the development of a vaccine.... -
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- Viscerotropic growth pattern of Leishmania tropica in BALB/c mice is suggestive of a murine model for human viscerotropic leishmaniasis
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Mahmoudzadeh-Niknam H, Kiaei SS, Iravani D
- KMID: 1089945
- Korean J Parasitol.
- 2007 Dec;45(4):247-253.
- doi: 10.3347/kjp.2007.45.4.247
Leishmania (L.) tropica is a causative agent of cutaneous leishmaniasis, and occasionally of visceral or viscerotropic leishmaniasis in humans. Murine models of Leishmania infection have been proven to be useful... -
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- Cutaneous Leishmaniasis of the Eyelids: A Case Series with Molecular Identification and Literature Review
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Mohammadpour I, Motazedian MH, Handjani F, Hatam GR
- KMID: 2367420
- Korean J Parasitol.
- 2016 Dec;54(6):787-792.
- doi: 10.3347/kjp.2016.54.6.787
Cutaneous leishmaniasis (CL) is a protozoan disease which is endemic in Iran. It is transmitted by the Phlebotomus sand fly. The eyelid is rarely involved possibly because the movement of... -
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- Miltefosine-Induced Apoptotic Cell Death on Leishmania major and L. tropica Strains
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Khademvatan S, Gharavi MJ, Rahim F, Saki J
- KMID: 1715628
- Korean J Parasitol.
- 2011 Mar;49(1):17-23.
- doi: 10.3347/kjp.2011.49.1.17
The aim of this study was to assess the cytotoxic effects of various concentrations of miltefosine on Leishmania major (MRHO/IR/75/ER) and L. tropica (MHOM/IR/02/Mash10) promastigotes and to observe the programmed... -
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- Production of nitric oxide by murine macrophages induced by lipophosphoglycan of Leishmania major
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Kavoosi G, Ardestani , Kariminia , Tavakoli Z
- KMID: 1091834
- Korean J Parasitol.
- 2006 Mar;44(1):35-41.
- doi: 10.3347/kjp.2006.44.1.35
Protozoan parasites of the genus Leishmania cause a number of important human diseases. One of the key determinants of parasite infectivity and survival is the surface glycoconjugate lipophosphoglycan (LPG). In... -
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- Identification of novel Leishmania major antigens that elicit IgG2a response in resistant and susceptible mice
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Mohammadi , Zeinali M, Ardestani , Kariminia
- KMID: 1091835
- Korean J Parasitol.
- 2006 Mar;44(1):43-48.
- doi: 10.3347/kjp.2006.44.1.43
Experimental murine models with high, intermediate and low levels of genetically based susceptibility to Leishmania major infection reproduce almost entire spectrum of clinical manifestations of the human disease. There are... -
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- Anti-leishmanial Effects of Trinitroglycerin in BALB/C Mice Infected with Leishmania major via Nitric Oxide Pathway
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Nahrevanian H, Najafzadeh M, Hajihosseini R, Nazem H, Farahmand , Zamani Z
- KMID: 1720619
- Korean J Parasitol.
- 2009 Jun;47(2):109-115.
- doi: 10.3347/kjp.2009.47.2.109
This study investigated whether trinitroglycerine (TNG) as nitric oxide (NO) releasing agent had anti-leishmanial effects and mediated pathology in BALB/c mice infected with Leishmania major. Cutaneous leishmaniasis (CL), a zoonotic... -
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- Tamoxifen Induces Apoptosis of Leishmania major Promastigotes in Vitro
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Doroodgar , Delavari M, Doroodgar , Abbasi A, Taherian A, Doroodgar
- KMID: 2374011
- Korean J Parasitol.
- 2016 Feb;54(1):9-14.
- doi: 10.3347/kjp.2016.54.1.9
Tamoxifen is an antagonist of the estrogen receptor and currently used for the treatment of breast cancer. The current treatment of cutaneous leishmaniasis with pentavalent antimony compounds is not satisfactory.... -
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- Effects of combined therapy with thalidomide and glucantime on leishmaniasis induced by Leishmania major in BALB/c mice
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Solgi G, Kariminia , Abdi K, Darabi M, Ghareghozloo B
- KMID: 1091837
- Korean J Parasitol.
- 2006 Mar;44(1):55-61.
- doi: 10.3347/kjp.2006.44.1.55
For treating Leishmania major infection in BALB/c mice, we used thalidomide in conjunction with glucantime. Groups of mice were challenged with 5 x 10(3) metacyclic promastigotes of L. major subcutaneously.... -
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- In Vitro Infectivity Assessment by Drug Susceptibility Comparison of Recombinant Leishmania major Expressing Enhanced Green Fluorescent Protein or EGFP-Luciferase Fused Genes with Wild-Type Parasite
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Sadeghi S, Seyed N, Etemadzadeh MH, Abediankenari S, Rafati S, Taheri T
- KMID: 2381755
- Korean J Parasitol.
- 2015 Aug;53(4):385-394.
- doi: 10.3347/kjp.2015.53.4.385
Leishmaniasis is a worldwide uncontrolled parasitic disease due to the lack of effective drug and vaccine. To speed up effective drug development, we need powerful methods to rapidly assess drug... -
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- Epidemiological Aspects of Cutaneous Leishmaniasis during 2009–2016 in Kashan City, Central Iran
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Moein D, Masoud D, Saeed M, Abbas D
- KMID: 2408520
- Korean J Parasitol.
- 2018 Feb;56(1):21-24.
- doi: 10.3347/kjp.2018.56.1.21
Cutaneous leishmaniasis (CL) can be seen in 2 forms, zoonotic and anthroponotic, in Iran. In this study, epidemiological aspects of CL were studied during an 8-year period (2009–2016) in city... -
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- Skin ulcer and immunoblot patterns by inoculation sites in BALB/c mice infected with Leishmania major
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Lee M, Lee JK, Kim SB, Lee SH, Hong ST
- KMID: 1715334
- Korean J Parasitol.
- 1997 Mar;35(1):31-38.
- doi: 10.3347/kjp.1997.35.1.31
The skin ulcer in Leishmania major infection is known to be variable according to the inoculation sites even in a susceptible host. The present study traced the immunoblot patterns by... -
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- Childhood cutaneous leishmaniasis: report of 117 cases from Iran
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Talari SA, Talaei R, Shajari G, Vakili Z, Taghaviardakani A
- KMID: 1088767
- Korean J Parasitol.
- 2006 Dec;44(4):355-360.
- doi: 10.3347/kjp.2006.44.4.355
Cutaneous leishmaniasis (CL), due to Leishmania major, is endemic in different parts of Iran and has long been recognized in most provinces of Iran. This study was conducted to determine... -
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- Evaluation of the Interventional Approaches in the Management of Cutaneous Leishmaniasis in Jazan: An Observational Study
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Makeen HA, Buraik MA, Menachery , Alattas KM, Meraya AM
- KMID: 2419748
- Ann Dermatol.
- 2018 Oct;30(5):575-580.
- doi: 10.5021/ad.2018.30.5.575
BACKGROUND: Cutaneous leishmaniasis is a tropical infection of public health importance. Numerous treatment approaches are in practice with variable degree of success however its management has no universal consensus or... -
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