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Connecting the dots between SHP2 and glutamate receptors

Ryu HH, Kim SY, Lee YS

SHP2 is an unusual protein phosphatase that functions as an activator for several signaling pathways, including the RAS pathway, while most other phosphatases suppress their downstream signaling cascades. The physiological...
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Spatial Learning and Motor Deficits in Vacuolar Protein Sorting-associated Protein 13b (Vps13b) Mutant Mouse

Kim MJ, Lee RU, Oh J, Choi JE, Kim H, Lee K, Hwang SK, Lee JH, Lee JA, Kaang BK, Lim CS, Lee YS

Vacuolar protein sorting-associated protein 13B (VPS13B), also known as COH1, is one of the VPS13 family members which is involved in transmembrane transport, Golgi integrity, and neuritogenesis. Mutations in the...
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Prevalence of Reading and Mathematical Learning Disabilities in Korean School-Aged Children of Jeju Region

Yoo HK, Huh H, Hong IH, Kim JH, Kim HJ, Cho S, Yang SJ, Jung J

OBJECTIVES: This study investigated the prevalence of reading and mathematical learning disabilities of students at primary schools in Jeju Island, South Korea. We examined major causes of learning disabilities including...
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A Survey for Mental Health of Children Whose Parents Have Psychiatric Disorders: A Preliminary Study for Mental Health Screening of High Risk Children

Seo HY, Park SM, Kim Y, Yang YH, Lee JY, Lee HW, Jung HY

OBJECTIVES: This study aimed to evaluate the mental health status of the children of psychiatric patients in order to plan for the resources that may be necessary to help these...
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Clinical Implications of Social Communication Disorder

Shin SH

Social (pragmatic) communication disorder (SCD) is a new diagnosis included under communication disorders in the neurodevelopmental disorders section of Diagnostic and Statistical Manual of Mental Disorders-5. SCD is defined as...
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A Novel SLC25A15 Mmutation Causing Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

Jang KM, Hyun MC, Hwang SK

Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH syndrome) is a neurometabolic disorder with highly variable clinical severity ranging from mild learning disability to severe encephalopathy. Diagnosis of HHH syndrome can easily be delayed or...
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Development of the Computerized Mathematics Test in Korean Children and Adolescents

Lee EK, Jung J, Kang SH, Park EH, Choi I, Park S, Yoo HK

OBJECTIVES: This study was conducted in order to develop a computerized test to measure the level of mathematic achievement and related cognitive functions in children and adolescents in South Korea. METHODS:...
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Communicator Frog, to be a Catcher or a Frog Itself

Bahn GH

No abstract available.
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Changes in Synaptic Transmission and Long-term Potentiation Induction as a Possible Mechanism for Learning Disability in an Animal Model of Multiple Sclerosis

Mosayebi G, Soleyman M, khalili M, Mosleh M, Palizvan M

PURPOSE: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. It has been shown that memory deficits is common in patients with MS. Recent studies...
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Brain-Derived Neurotrophic Factor (BDNF) Exerts a Protective Effect via an Anti-Apoptotic Mechanism on Hypoxic-Ischemic Injury in the Rat Brain

Kim BJ, Lee HS, Han YH, Jeong JE, Lee EJ, Choi EJ, Kim WT

PURPOSE: Perinatal hypoxic-ischemic (HI) brain injury remains a common cause of chronic handicapping conditions of cerebral palsy, mental retardation, learning disability, and epilepsy. HI brain injury induces cell death via...
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Psychological Assessment in Neurodevelopmental Disorders

Oh MY

Neurodevelopmental disorders are characterized by impaired development that causes adjustment problems. The spectrum of developmental impairment varies and includes intellectual disabilities, communication and social interaction challenges, and attention and executive...
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Roles of mTOR Signaling in Brain Development

Lee DY

mTOR is a serine/threonine kinase composed of multiple protein components. Intracellular signaling of mTOR complexes is involved in many of physiological functions including cell survival, proliferation and differentiation through the...
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Introduction of the Concept of Social Dysfunction Spectrum

Bahn GH, Lee YJ, Han J

Along with language, socialization is a unique feature of the human being. There is a continuous debate regarding whether the development of socialization is innate, and conducted by the environment...
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An Exploratory Study of Parents' Perceived Educational Needs for Parenting a Child with Learning Disabilities

Chien WT, Lee IY

  • KMID: 2268142
  • Asian Nurs Res.
  • 2013 Mar;7(1):16-25.
PURPOSE: This exploratory, qualitative study was conducted to explore Chinese couples' perceived educational needs for parenting a child with specific learning difficulties (SLD). METHODS: We recruited a purposive sample of 25...
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Treatment of Developmental Disorders with ADHD Symptoms

Kim GM, Ahn DH, Shin SH, Suh DS, Yoo HJ, Kim YK

  • KMID: 2172668
  • J Korean Acad Child Adolesc Psychiatry.
  • 2012 Oct;23(Suppl):S66-S71.
Developmental disorders such as mental retardation, autism spectrum disorders, and learning disorders are frequently associated with attention-deficit/hyperactivity disorder (ADHD) symptoms such as inattention, hyperactivity, and impulsivity. The existing data for...
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The Comorbidity of Attention Deficit Hyperactivity Disorder in Children with Epilepsy

Sim GY, Son JW, Kim WS

  • KMID: 2059492
  • J Korean Child Neurol Soc.
  • 2012 Sep;20(3):129-136.
PURPOSE: Attention Deficit Hyperactivity Disorder (ADHD) is known to be more common in children with epilepsy than in the general population. Thirty one to forty percent of ADHD is accompanied...
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Impact of allergic rhinitis in school going children

Mir E, Panjabi C, Shah A

Allergic rhinitis (AR) is the most common chronic pediatric disorder. The International Study for Asthma and Allergies in Childhood phase III found that the global average of current rhinoconjunctivitis symptoms...
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The Analysis of Intervention Studies for Snoezelen

Park YR, Oh DN, Kim KS, Kim JA, Wee H

  • KMID: 2287950
  • Korean J Rehabil Nurs.
  • 2011 Dec;14(2):95-102.
PURPOSE: The purpose of this study was to analyze intervention studies related to Snoezelen (multisensory environment). METHODS: Studies related to Snoezelen (multisensory environment) published between 1995 and 2010 in both Korean...
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Differences in Sleep Patterns are Related to Behavior, Emotional Problems, Attention and Academic Performance in Elementary School Students of a South Korean Metropolitan City

Tak HJ, Lee JH, Lee CM, Chung SH, Lee JW, Sim CS, Yoon JG, Sung JH, Bhang SY

  • KMID: 2291677
  • J Korean Acad Child Adolesc Psychiatry.
  • 2011 Sep;22(3):182-191.
OBJECTIVES: The aim of this study was to investigate the sleep patterns of South Korean elementary school children and whether the differences in sleep patterns were related to behavior, emotional...
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A case of McKusick-Kaufman syndrome

Son SH, Kim YJ, Kim ES, Kim EK, Kim HS, Kim BI, Choi JH

McKusick-Kaufman syndrome (MKS) is an autosomal recessive multiple malformation syndrome characterized by hydrometrocolpos (HMC) and postaxial polydactyly (PAP). We report a case of a female child with MKS who was...
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