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Report on the External Quality Assessment Scheme for Genetic Disorders and Other Human Genetics Molecular Diagnostics in Korea (2018–2021)

Lee H, Kim B, Kim MJ, Lee JS, Cho SI, Shin HS, Seong MW

The human genetics molecular diagnostic proficiency testing program of the Korean Association of Quality Assurance for Clinical Laboratory conducted two trials annually from 2018–2021. The program consisted of the same...
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A Pilot Project for the Expansion of the External Quality Assessment Program in Transfusion Medicine: Anti-D Titer Test

Chung Y, Kim JS, Youk HJ, Hwang SH, Oh HB, Kim H, Ko DH

Background: Many test items in transfusion medicine that are still not included in the Korean Association of External Quality Assessment Service. We performed a pilot project of anti-D titer test for...
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Establishment of Critical Difference for Diagnostic Immunoassays

Yu S, Moon SY, Shin KH, Lee SM, Park CM, Jun KR

Background: Critical difference (CD) is a significant difference between sequential laboratory results in a patient and is a major parameter for comparative evaluation of quantitative clinical laboratory tests, and how...
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Commutability Assessment of Frozen Human Serum Pools for External Quality Assessment of Tumor Markers

Cho Ej, Kim SH, Hong J, Lee H, Hyun J, Cho SE, Lee W, Kim HS, Oh EJ, Chun S, Min WK

Background: Commutability is essential to harmonize different measuring systems and to evaluate the performance of participating laboratories in external quality assessment (EQA). This study aims to assess the com mutability...
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Detection of ASXL1 Codon 646 Variant Using Amplicon-Based Next-Generation Sequencing

Kim M, Kim NY, Hong S, Lee J, Cho Y, Kim HS, Kang HJ, Lee YK

Background: The ASXL1 codon 646 variant is the most common ASXL1 variant that negatively impacts the prognoses of patients with myeloid malignancies, particularly those with myelodysplastic syndromes and acute myeloid...
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Apolipoprotein E Genotyping Using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism with General-Purpose Agarose and Lithium Borate Buffer

Oh K, Park G

Background: Apolipoprotein E (APOE ) genotyping is an important test for predicting the risk of Alzheimer’s and cardiovascular disease. The polymerase chain reaction-restriction fragment length polymorphism (PCRRFLP) technique for APOE...
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Evaluation of SARS-CoV-2 Molecular Test Using Saliva and Anterior Nasal Swab Samples Compared with Conventional Nasopharyngeal Swab Samples

Chang J, Lee SS, Kim DH, Kim S

Background: As the global pandemic of severe acute respiratory syndrome coronavirus-2 continues, so does the need for molecular tests with simple, painless, and easy sample collection. We aimed to investigate...
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