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The First Case of Extensively Drug-resistant Salmonella Typhi in South Korea

Lee NY, Ham JY, Song KE, Kim S

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Comparison and Recommendation of Diagnostic Tools for Bacterial Pharyngitis at Primary Care Clinics

Jo SA, Kim S

There are more than 10 million visits to primary care clinics annually due to pharyngitis or tonsillitis. The antibiotic prescription rate for these patients is more than 50%. An optimal...
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Vancomycin and Aminoglycoside Antibiotic Drug Concentration Measurement: Current Status in Clinical Laboratories in Korea

Kwon WK, Oh J, Lee SY, Park HD

Background: Therapeutic drug monitoring (TDM) is clinically recommended for vancomycin and aminoglycoside antibiotics owing to their narrow therapeutic range and nephrotoxicity at high concentrations in the blood. This study was...
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Emergence of Monosomy 7 in Philadelphia-Negative Cells during MDS Development and not CML Diagnosis Proved by Serial Droplet Digital PCR

Park S, Mun YC, Seong CM, Huh J

Emergence of new clonal chromosomal abnormality (CCA) has been reported in Philadelphia-negative cells in patients with chronic myeloid leukemia (CML) undergoing the tyrosine kinase inhibitor (TKI) treatment. However, the time...
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A Case of Partial D Type VI-3 Confirmed by RHD Genotyping

Lee JK, Yu H, Chung YN, Bae JC, Cho D

Weak D and partial D result in quantitative and qualitative changes in RhD protein expression respectively. It is difficult to discriminate weak D from partial D by serological tests alone....
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Turnaround Time (TAT) Setting Status of 30 Domestic Clinical Laboratories and Consideration for Improvement and Management of TAT

Cho HE, Kim YJ, Kim JH, Kim S, Lee YW, Cho SY

Background: Turnaround time (TAT) is a major quality control indicator and can be defined differently depending on the starting point in the examination process. To determine effective TAT management plan,...
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Elimination of Anti-CD47 Interference in Pretransfusion Testing by Multiple Platelet Alloadsorption: A Case Report

Lee H, Kim YJ, Kim JS, Yang JJ, Hwang SH, Oh HB, Ko DH

Hu5F9-G4, an immunoglobulin 4 (IgG4) monoclonal humanized antibody targeting CD47, is under active clinical trials as a novel immunotherapeutic for hematologic and solid malignancies and can cause pretransfusion testing interference....
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Comparison of Clinical Utility between Phadiatop Assay and AdvanSureTM AlloScreen

Kim MK, Kwon MJ, Park H, Woo HY

Background: Multiple Allergo-Sorbent Test (MAST) allows simultaneous detection of specific IgE antibodies using multiple allergens, and it is commonly used for allergy screening. Phadiatop assay (Phadia AB, Sweden), including Phadiatop...
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The Usefulness of Flow Cytometry for Measuring Phosphorylated Signal Transducer and Activator of Transcription 1 to Diagnose and Manage Chronic Mucocutaneous Candidiasis: A Case Report

Yoon SJ, Kwon WK, Jeong M, Yeon JH, Huh HJ, Lee NY, Kim YJ, Kang ES

Autosomal dominant chronic mucocutaneous candidiasis (AD-CMC) is a subtype of CMC caused by gain-of-function (GOF) mutation of the signal transducer and the activator of transcription 1 (STAT1) protein. GOF mutation...
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Correlation Between C3d Assay and Single Antigen Bead Assay for Detection of Human Leukocyte Antigen Class II Antibodies

Kang H, Kim DH, Ha JS, Ryoo N, Jeon DS, Lee W

Background: Detection of anti-human leukocyte antigen (HLA) antibodies is important during the selection of an appropriate donor prior to organ transplantation and also for monitoring the patients after transplantation. In...
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Comparison of IRIS Iq200, UF-1000i, and Cobas u701 Module Automated Urine Sediment Analyzers

Choi H, Yang D, Kwon SJ, Kang PR, Park H, Kim T, Hwang H

Background: We sought to compare the performance of three commercially available automated urine sediment analyzers that represent the current urine sediment analysis technology. Methods: A total of 232 patient samples were...
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Utility of Plasma Cell Screening Tube Kit to Differentiate Neoplastic Plasma Cells from Reactive Plasma Cells

Bang HI, Choi TY

Flow cytometry is a powerful tool for analysis of hematologic malignancies, that provides rapid, quantitative, and multiparametric analysis of heterogeneous cell populations, but requires standardization because of complexities in panel...
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