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Two Clinical Cases of Anti-Di(b) with Di(a+b-) Phenotypes: Practical Need for Rare Blood Donor Registry Program in Korea

Lee MY, Park TS, Oh SH, Kim S, Kim HO

Here, we report two cases of identified anti-Di(b) antibodies with rare Di(a+b−) blood types from two different hospitals in Korea. Di(b) mismatched transfusion could cause a hemolytic transfusion reaction. However,...
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Origins and History of Laboratory Medicine

Lee HJ, Oh SH, Chang CL

Medical diagnostics plays a significant role in clinical decisions. The first medical laboratory test to be developed was urine analysis, in which urine properties were analyzed for diagnosis. Urine analysis...
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Analytical Performance of Bio-Rad D-100 on a Hemoglobin A1c Assay

Liu C, Choi E, Bae IC, Lee SG, Kim JH

BACKGROUND: Hemoglobin A1c (HbA1c) is considered a marker useful for the follow-up and diagnosis of diabetes and implies the importance of reliable assay methods that are traceable to a reference...
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A Case of Pseudohypoparathyroidism Type Ib Caused by Aberrant Methylation in the GNAS Complex Locus

Jo SJ, Han E, Jang W, Chae H, Kim Y, Lee GD, Cho WK, Suh BK, Kim M

Pseudohypoparathyroidism (PHP) is a rare disorder caused by genetic and epigenetic aberrations in the GNAS complex locus resulting in impaired expression of stimulatory G protein (Gsα). PHP type Ib (PHP-Ib)...
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Proposal of Modified HIL-indices for Determining Hemolysis, Icterus and Lipemia Interference on the Beckman Coulter AU5800 Automated Platform

Lim YK, Cha YJ

BACKGROUND: The amount of interference due to hemolysis, bilirubin, and lipemia can be measured on the AU5800 autoanalyzer (Beckman Coulter, USA) by spectrophotometry. This is reported as semi-quantitative indices, specifically...
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Comparison and Evaluation of Diagnostic Assays for Clostridium difficile Infection

Kim KB, Kim DH, Lee W, Ha JS, Ryoo NH, Jeon DS, Kim JR

BACKGROUND: Clostridium difficile is a leading causative microorganism of pseudomembranous colitis (PMC) and antibiotic-associated diarrhea. In patients who have a history of antibiotic use and diarrhea, the presence of the...
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