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Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines Part 1

Kim S, Yun YM, Kim IS, Song SH, Woo HI, Lee KA, Lee W, Cho HJ, Ji M, Chae HJ, Lee SY, Chun S

Pharmacogenetics is a rapidly evolving field, and the number of pharmacogenetic tests for clinical use is steadily increasing. However, incorrect or inadequate implementation and use of pharmacogenetic testing in clinical...
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A Rare der(Y)t(Y;1)(q12;q12) in a Patient with Essential Thrombocythemia

Lim HH, Choi JL, Kim BR, Woo KS, Kim KH, Kim JM, Kim SH, Han JY

Among hematologic diseases, structural abnormalities of autosomal chromosomes are well-known, but cases involving the sex chromosomes are uncommon. Duplications of the long arm of chromosome 1 have been reported in...
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Performance Evaluation of the CLINITEK Novus Automated Urine Chemistry Analyzer

Yim J, Lee SG, Cho S, Won YC, Kim JH

BACKGROUND: We aimed to evaluate the performance of the CLINITEK Novus urine chemistry analyzer (Siemens, UK). METHODS: The precision, correlation, and carryover study were performed using two kinds of commercial quality...
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Therapeutic Leukapheresis for the Management of Hyperleukocytosis: Ten-year Experience in a Tertiary Care Hospital

Kim B, Lee K, Kim S, Kim HO

BACKGROUND: Hyperleukocytosis is a medical emergency that is characterized by increased blood viscosity and predisposition to various neurological, pulmonary, and gastrointestinal complications. In addition, patients are at risk of the...
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Performance Evaluation of Automated Clinical Chemistry Analyzer for Indocyanine Green (ICG) R15 Test

Park JH, Won EJ, Choi HJ, Kee SJ, Suh SP

BACKGROUND: The conventional indocyanine green retention rate at 15 minutes (ICG R15) test is inefficient and inconvenient because it requires the use of a manual spectrophotometer and several samples per...
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A Case of Septic Shock Following Catheter-related Infection Caused by Lactococcus lactis subsp. lactis in an Adult

Bae TW, Lee J, Lee HS, Cho YG

Lactococcus lactis is a gram-positive cocci used extensively in the dairy industry, but considered an unusual pathogen in humans. Among its five subspecies, L. lactis subsp. lactis in particular has...
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Comparing the Efficacy of Samsung LABGEO PT10 and Bio-Rad Variant II Turbo for HbA1c Measurement in Three Types of Blood Samples

Park JE, Park HD

BACKGROUND: Hemoglobin A1c (HbA1c) is a good marker for monitoring glycemic control. The Samsung LABGEO PT10 HbA1c test (Samsung Electronics, Korea) was developed as a point-of-care testing approach. This study...
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Nucleic Acid Extraction for the Quantification of Cytomegalovirus and Epstein-Barr Virus

Sung H, Hwang SH, Koh YJ, Kim MN

BACKGROUND: Availability of an international standard will improve the standardization of quantitative PCR (qPCR) for cytomegalovirus (CMV) and Epstein-Barr virus (EBV); however, nucleic acid extraction methods may affect qPCR results....
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Association between Glycemic Control and Hematologic Indices in Type 2 Diabetic Patients

Oh Y, Kwon GC, Koo SH, Kim J

BACKGROUND: Diabetes mellitus (DM) is characterized by impaired glucose regulation and various complications. It is known that chronic inflammation and platelet activation play a role in development of insulin resistance...
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Clinical Usefulness of a DNA Microarray-based Assay for the Diagnosis of Sexually Transmitted Infections

Park AJ, Kim SY, Seo DH

BACKGROUND: Many molecular diagnostic methods have been developed to detect sexually transmitted infections (STI). The STDetect Chip (LabGenomics, Korea) which is a DNA microarray-based tool, newly developed for STI diagnosis...
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Comprehensive Analysis of Blood Cultures Using BacT/Alert 3D FA Plus and FN Plus Media

Byun JH, Kim SW, Koh EH, Kim S, Kim SC

BACKGROUND: We prospectively evaluated the performance of blood culture resin media, FA Plus and FN Plus, of the BacT/Alert 3D System (bioMérieux Inc., USA) in a tertiary university-affiliated hospital. METHODS: We...
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