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Characteristic visual phenotypes in Korean wild mice (KWM/Hym)

Jamiyansharav M, Shin H, Kim B, Kim H, Han SJ, Seong JK, Suh JG, Seo KY

Background In the last few decades, numerous efforts have been made to develop a better mouse model to overcome the current limitations of laboratory inbred mouse models such as have...
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Role of pentoxifylline in neonatal hypoxic ischaemic encephalopathy: a systematic review of animal studies

Wong F, Rath C, Gowda B, Patole S

We systematically reviewed the evidence from animal studies assessing the effects of pentoxifylline on neonatal hypoxic-ischemic encephalopathy (HIE). The PubMed, EMBASE, EMCARE, MEDLINE, Cochrane Library, and Google Scholar databases were searched for randomized and quasi randomized controlled trials...
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Immune deficiency phenotypes of Il2rg, Rag2 or Il2rg/Rag2 double knockout rats; establishment of human leukemia xenograft models

Kim J, Lim H, Kwon E, Mashimo T, Kang B

Background Genetically immunodeficient mice lacking Il2rg and Rag2 genes have been widely utilized in the field of biomedical research. However, immunodeficient rats, which offer the advantage of larger size, have not been as extensively used to date. Recently, Severe...
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Antigenicity evaluation of lac color and exploratory study for identifying potential biomarkers of anaphylaxis

Lim H, Han K, Kim S, Ryu S, You J, Yoon J, Kwon E, Kim J, Kang B

Background Lac color, a natural red dye derived from the larvae of laccifer lacca kerr, is one of the most commonly used substances in food. To date, no studies have reported on the antigenicity of lac color and the other biomarkers that can determine anaphylactic...
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Cleistopholis patens root bark extract exerts cardioprotective effect against doxorubicin‑induced myocardial toxicity in rats

Ononiwu C, Joshua P, Amah C, Asomadu R, Okorigwe E, Nnemolisa C, Ezeorba T, Nwanelo V, Iyidiegwu F, Duru J, Okeke P, Adiele O

Background Myocardial Infarction still persists as the most prevalent cardiovascular disease and is a top cause of morbidity and mortality in doxorubicin treated cancer patients. This study evaluated the prophylactic effect of the ethanol root bark extract of Cleistopholis patens (ERBECP)...
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Observation of neutrophil extracellular traps in the development of diabetic nephropathy using diabetic murine models

Jeon YH, Oh SH, Jung SJ, Oh EJ, Lim JH, Jung HY, Choi JY, Park SH, Kim CD, Kim YL, Hong CW, Cho JH

Background Diabetic nephropathy (DN) is a progressive complication among patients with diabetes and the most common cause of end-stage kidney disease. Neutrophil extracellular traps (NETs) are known to play a...
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Hypoxia‑inducible factor‑1α‑deficient adipose‑tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein‑1

Kang G, Kim Y, Oh H, Jo H, Bok S, Jeon Y, Cheon G, Roh T, Chang Y, Park D, Ahn G

Background Uncoupling protein 1 (UCP1) is a proton uncoupler located across the mitochondrial membrane gener‑ ally involved in thermogenesis of brown adipose tissues. Although UCP1 is known to be strongly expressed in brown adipocytes, recent evidence suggest that white adipocytes...
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Correction: Effects of single housing on behavior, corticosterone level and body weight in male and female mice

Smolensky I, Zajac-Bakri K, Mallien AS, Gass P, Guzman R, Inta D

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