- Ventilator-induced lung-injury in mouse models: Is there a trap?
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Joelsson JP, Ingthorsson S, Kricker J, Gudjonsson T, Karason S
- KMID: 2523771
- Lab Anim Res.
- 2021 Dec;37(4):266-276.
- doi: 10.1186/s42826-021-00108-x
Ventilator-induced lung injury (VILI) is a serious acute injury to the lung tissue that can develop during mechanical ventilation of patients. Due to the mechanical strain of ventilation, damage can... -
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- Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study
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Cho DW, Han HY, Yang MJ, Woo DH, Han SC, Yang YS
- KMID: 2523776
- Lab Anim Res.
- 2021 Dec;37(4):320-323.
- doi: 10.1186/s42826-021-00106-z
Background: Telemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device,... -
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- Inflammatory response in the mid colon of ICR mice treated with polystyrene microplastics for two weeks
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Choi YJ, Kim JE, Lee SJ, Gong JE, Jin YJ, Seo S, Lee JH, Hwang DY
- KMID: 2523773
- Lab Anim Res.
- 2021 Dec;37(4):285-293.
- doi: 10.1186/s42826-021-00109-w
Background: The oral administration of polystyrene-microplastics (PS-MPs) causes chronic constipation of ICR mice, but there are no reports on their effects on the inflammatory response in the colon. To determine... -
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- Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice
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Yun WB, Kim JE, Lee ML, Choi JY, Park JJ, Song BR, Kang BC, Nam KT, Lee HW, Hwang DY
- KMID: 2523774
- Lab Anim Res.
- 2021 Dec;37(4):294-306.
- doi: 10.1186/s42826-021-00107-y
Background: This study was undertaken to compare the sensitivities of mice strains during tumor induction by transcription activator-like effector nucleases (TALEN)-mediated Trp53 mutant gene. Alterations of their tumorigenic phenotypes including... -
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- Comparison of cisplatin-induced anti-tumor response in CT26 syngeneic tumors of three BALB/c substrains
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Gong JE, Jin YJ, Kim JE, Choi YJ, Lee SJ, Kim KS, Jung YS, Cho JY, Lim Y, Kang HG, Hwang DY
- KMID: 2523775
- Lab Anim Res.
- 2021 Dec;37(4):307-319.
- doi: 10.1186/s42826-021-00110-3
Background: To determine whether the background of BALB/c substrains affects the response to anti-tumor drugs, we measured for alterations in tumor growth, histopathological structure of the tumor, and expressions of... -
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- Reduced receptor for advanced glycation end products is associated with α-SMA expression in patients with idiopathic pulmonary fibrosis and mice
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Baek H, Jang S, Park J, Jang J, Lee J, Hong SH, Kim WJ, Park SM, Yang SR
- KMID: 2523772
- Lab Anim Res.
- 2021 Dec;37(4):277-284.
- doi: 10.1186/s42826-021-00105-0
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease. Despite alveolar epithelial cells is crucial role in lung, its contribution and the associated biomarker remain unknown... -
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