- Retraction Note: Effects of DA-5513 on alcohol metabolism and alcoholic fatty liver in rats
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Yu JY, Nguyen HT, Yong CS, Park HG, Jun JH, Kim JO
- KMID: 2506043
- Lab Anim Res.
- 2020 Jun;36(2):145-145.
- doi: 10.1186/s42826-020-00047-z
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- Animal models for the risk assessment of viral pandemic potential
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Park MS, Kim JI, Bae JY, Park MS
- KMID: 2506034
- Lab Anim Res.
- 2020 Jun;36(2):73-87.
- doi: 10.1186/s42826-020-00040-6
Pandemics affect human lives severely and globally. Experience predicts that there will be a pandemic for sure although the time is unknown. When a viral epidemic breaks out, assessing its... -
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- Zebrafish as an alternative animal model in human and animal vaccination research
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Bailone RL, Fukushima HCS, Fernandes BHV, Aguiar LKD, Corrêa T, Janke H, Setti PG, Oliveira Roça RD, Borra RC
- KMID: 2506036
- Lab Anim Res.
- 2020 Jun;36(2):98-107.
- doi: 10.1186/s42826-020-00042-4
Much of medical research relies on animal models to deepen knowledge of the causes of animal and human diseases, as well as to enable the development of innovative therapies. Despite... -
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- Highlights on selected microscopy techniques to study zebrafish developmental biology
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Abu-Siniyeh A, Al-Zyoud W
- KMID: 2506035
- Lab Anim Res.
- 2020 Jun;36(2):88-97.
- doi: 10.1186/s42826-020-00044-2
Bio-imaging is a tedious task when it concerns exploring cell functions, developmental mechanisms, and other vital processes in vivo. Single-cell resolution is challenging due to different issues such as sample... -
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- Enhanced alcohol degradation and hepatic protective effects of an Acetobacter Pasteurianus-derived product, CureZyme-ACE, in an acute intoxication rat model
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Jeon EJ, Cho YS, Kim AH, Shim JM, Kim YS, Piao Z, Shin YC, Kwon J
- KMID: 2506039
- Lab Anim Res.
- 2020 Jun;36(2):126-133.
- doi: 10.1186/s42826-020-00050-4
Excessive alcohol consumption induces acute intoxication and various hepatic diseases. In this study, we investigated the effect of the CureZyme-ACE (CA), Acetobacter Pasteurianus (AP)-derived product, in acute intoxication rats. The... -
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- Therapeutic potential of stem cell-derived extracellular vesicles in osteoarthritis: preclinical study findings
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Kim KH, Jo JH, Cho HJ, Park TS, Kim TM
- KMID: 2506033
- Lab Anim Res.
- 2020 Jun;36(2):66-72.
- doi: 10.1186/s42826-020-00043-3
Extracellular vesicles (EVs) are nano-sized particles secreted by almost all cell types, and they mediate various biological processes via cell-to-cell communication. Compared with parental cells for therapeutic purposes, stem cell-derived... -
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- Evaluation of canine teeth crown reduction technique in macaques
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Kim SM, Kim JM
- KMID: 2506041
- Lab Anim Res.
- 2020 Jun;36(2):140-144.
- doi: 10.1186/s42826-020-00051-3
Background:The reduction of canine teeth in adult males in whom permanent canine teeth eruption occurs should be considered due to the safety of humans or other monkeys. The objective of... -
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- Synaptic loss and amyloid beta alterations in the rodent hippocampus induced by streptozotocin injection into the cisterna magna
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Ahn Y, Seo J, Park J, Won J, Yeo HG, Kim K, Jeon CY, Huh JW, Lee SR, Lee DS, Lee Y
- KMID: 2506040
- Lab Anim Res.
- 2020 Jun;36(2):134-139.
- doi: 10.1186/s42826-020-00049-x
To date, researchers have developed various animal models of Alzheimer’s disease (AD) to investigate its mechanisms and to identify potential therapeutic treatments. A widely recognized model that mimics the pathology... -
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- Rodent models for psychiatric disorders: problems and promises
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Baker M, Hong SI, Kang S, Choi DS
- KMID: 2504382
- Lab Anim Res.
- 2020 Jun;36(2):56-65.
- doi: 10.1186/s42826-020-00039-z
Psychiatric disorders are a prevalent global health problem, over 900 million individuals affected by a continuum of mental and substance use disorders. Due to this high prevalence, and the substantial... -
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- Patient-derived xenografts as compatible models for precision oncology
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Cho SY
- KMID: 2506037
- Lab Anim Res.
- 2020 Jun;36(2):108-118.
- doi: 10.1186/s42826-020-00045-1
Cancer is a very heterogeneous disease, displaying heterogeneity between patients (inter-tumoral heterogeneity) and heterogeneity within a patient (intra-tumoral heterogeneity). Precision oncology is a diagnostic and therapeutic approach for cancers based... -
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- Decrease of 14–3-3 proteins by glutamate exposure in the cerebral cortex of newborn rats
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Kang JB, Lee SY, Park DJ, Koh PO
- KMID: 2506038
- Lab Anim Res.
- 2020 Jun;36(2):119-125.
- doi: 10.1186/s42826-020-00041-5
Glutamate is a representative excitatory neurotransmitter. However, excessive glutamate exposure causes neuronal cell damage by generating neuronal excitotoxicity. Excitotoxicity in neonates caused by glutamate treatment induces neurological deficits in adults.... -
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