- Organ-on-a-chip and the kidney
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Kim S, Takayama S
- KMID: 2381537
- Kidney Res Clin Pract.
- 2015 Sep;34(3):165-169.
- doi: 10.1016/j.krcp.2015.08.001
Traditional approaches to pathophysiology are advancing but still have many limitations that arise from real biologic systems and their associated physiological phenomena being too complicated. Microfluidics is a novel technology... -
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- Recent Progress in Lab-on-a-Chip Technology and Its Potential Application to Clinical Diagnoses
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Lee NY
- KMID: 2232849
- Int Neurourol J.
- 2013 Mar;17(1):2-10.
We present the construction of the lab-on-a-chip (LOC) system, a state-of-the-art technology that uses polymer materials (i.e., poly[dimethylsiloxane]) for the miniaturization of conventional laboratory apparatuses, and show the potential use... -
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- Fabrication of Polymerase Chain Reaction Plastic Lab-on-a-Chip Device for Rapid Molecular Diagnoses
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Trinh KT, Zhang H, Kang DJ, Kahng SH, Tall BD, Lee NY
- KMID: 2309838
- Int Neurourol J.
- 2016 May;20(Suppl 1):S38-S48.
PURPOSE: We aim to fabricate a thermoplastic poly(methylmethacrylate) (PMMA) Lab-on-a-Chip device to perform continuous- flow polymerase chain reactions (PCRs) for rapid molecular detection of foodborne pathogen bacteria. METHODS: A miniaturized plastic... -
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- Applications of Microfluidic Devices for Urology
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Han SJ, Park HK, Kim KS
- KMID: 2378432
- Int Neurourol J.
- 2017 Apr;21(Suppl 1):S4-S9.
- doi: 10.5213/inj.1734838.419
Microfluidics is considered an important technology that is suitable for numerous biomedical applications, including cancer diagnosis, metastasis, drug delivery, and tissue engineering. Although microfluidics is still considered to be a... -
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- Neural Stem Cell Differentiation Using Microfluidic Device-Generated Growth Factor Gradient
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Kim JH, Sim J, Kim HJ
- KMID: 2420389
- Biomol Ther.
- 2018 Jul;26(4):380-388.
- doi: 10.4062/biomolther.2018.001
Neural stem cells (NSCs) have the ability to self-renew and differentiate into multiple nervous system cell types. During embryonic development, the concentrations of soluble biological molecules have a critical role... -
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- Microfluidic System Based High Throughput Drug Screening System for Curcumin/TRAIL Combinational Chemotherapy in Human Prostate Cancer PC3 Cells
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An D, Kim K, Kim J
- KMID: 2170631
- Biomol Ther.
- 2014 Jul;22(4):355-362.
We have developed a fully automated high throughput drug screening (HTDS) system based on the microfluidic cell culture array to perform combinational chemotherapy. This system has 64 individually addressable cell... -
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- Relationship between Pericytes and Endothelial Cells in Retinal Neovascularization: A Histological and Immunofluorescent Study of Retinal Angiogenesis
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Choi SH, Chung M, Park SW, Jeon NL, Kim JH, Yu YS
- KMID: 2402723
- Korean J Ophthalmol.
- 2018 Feb;32(1):70-76.
- doi: 10.3341/kjo.2016.0115
PURPOSE: To evaluate the relationship between pericytes and endothelial cells in retinal neovascularization through histological and immunofluorescent studies. METHODS: C57BL/6J mice were exposed to hyperoxia from postnatal day (P) 7 to... -
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- Indirect Co-Culture of Stem Cells from Human Exfoliated Deciduous Teeth and Oral Cells in a Microfluidic Platform
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Kang KJ, Ju SM, Jang YJ, Kim J
- KMID: 2382942
- Tissue Eng Regen Med.
- 2016 Aug;13(4):428-436.
- doi: 10.1007/s13770-016-0005-2
Oral epithelial-mesenchymal interactions play a key role in tooth development and assist differentiation of dental pulp. Many epithelial and mesenchymal factors in the microenvironment influence dental pulp stem cells to... -
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- Flow Shear Stress Enhances the Proliferative Potential of Cultured Radial Glial Cells Possibly Via an Activation of Mechanosensitive Calcium Channel
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Park MG, Jang H, Lee SH, Lee CJ
- KMID: 2376574
- Exp Neurobiol.
- 2017 Apr;26(2):71-81.
- doi: 10.5607/en.2017.26.2.71
Radial glial cells (RGCs) which function as neural stem cells are known to be non-excitable and their proliferation depends on the intracellular calcium (Ca²âº) level. It has been well established... -
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