- Hypericum Perforatum Decreased Hippocampus TNF-alpha and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats
-
El-Bakly W, Hasanin AH
- KMID: 2285515
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):233-239.
- doi: 10.4196/kjpp.2014.18.3.233
The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-alpha levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to 17alpha... -
- CITED
-
- Close
- SHARE
-
- Close
- High-Fat Diet and Voluntary Chronic Aerobic Exercise Recover Altered Levels of Aging-Related Tryptophan Metabolites along the Kynurenine Pathway
-
Lee KJ, Jung KH, Cho JY, Lee ST, Kim HS, Shim JH, Lee SK, Kim M, Chu K
- KMID: 2383782
- Exp Neurobiol.
- 2017 Jun;26(3):132-140.
- doi: 10.5607/en.2017.26.3.132
Tryptophan metabolites regulate a variety of physiological processes, and their downstream metabolites enter the kynurenine pathway. Age-related changes of metabolites and activities of associated enzymes in this pathway are suggestable... -
- CITED
-
- Close
- SHARE
-
- Close
- Neopterin Levels and Indoleamine 2,3-Dioxygenase Activity as Biomarkers of Immune System Activation and Childhood Allergic Diseases
-
Ünüvar S, Erge D, Kılıçarslan B, Gözükara Bağ HG, Çatal F, Girgin G, Baydar T
- KMID: 2431606
- Ann Lab Med.
- 2019 May;39(3):284-290.
- doi: 10.3343/alm.2019.39.3.284
BACKGROUND: Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase with interferon-gamma (IFN-γ) stimulation. We investigated... -
- CITED
-
- Close
- SHARE
-
- Close
- A Neurodegenerative Hypothesis of Cytokine-Serotonin Interaction in Major Depression
-
Kim YK
- KMID: 2341023
- J Korean Neuropsychiatr Assoc.
- 2004 Jul;43(4):386-392.
A growing body of evidence suggests that major depression is associated with increased productions of pro-inflammatory cytokines such as IL-1, IL-6, IL-12 or TNF-alpha and increased concentrations of prostaglandin E2... -
- CITED
-
- Close
- SHARE
-
- Close
- Values of Cytokines and Tryptophan Metabolites over a 12 Weeks Time Course in Patients with Depression and Somatoform Disorder
-
Krause D, Kirnich VB, Stapf TM, Hennings A, Riemer S, Riedel M, Schmidmaier R, Gil FP, Rief W, Schwarz MJ
- KMID: 2441631
- Clin Psychopharmacol Neurosci.
- 2019 Feb;17(1):34-42.
- doi: 10.9758/cpn.2019.17.1.34
OBJECTIVE: Previous studies have suggested alterations in the kynurenine pathway as a major link between cytokine and neurotransmitter abnormalities in psychiatric disorders. Most of these studies used a cross-sectional case-control... -
- CITED
-
- Close
- SHARE
-
- Close
- Convergence of Cancer Metabolism and Immunity: an Overview
-
Van Dang C, Kim JW
- KMID: 2400809
- Biomol Ther.
- 2018 Jan;26(1):4-9.
- doi: 10.4062/biomolther.2017.194
Cancer metabolism as a field of research was founded almost 100 years ago by Otto Warburg, who described the propensity for cancers to convert glucose to lactate despite the presence... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of COX-2 and IDO by Uteroglobin Transduction in NSCLC Cell Lines
-
Park GM, Lee SM, Yim JJ, Yang SC, Yoo CG, Lee CT, Han SK, Shim YS, Kim YW
- KMID: 2319164
- Tuberc Respir Dis.
- 2009 Apr;66(4):274-279.
BACKGROUND: Uteroglobin (UG) is a secretary protein that has strong immunomodulatory properties, and which is synthesized in most epithelia including lung tissue. Overexpression of UG is associated with decreased expression... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of Indoleamine 2,3-Dioxygenase Enhances the Therapeutic Efficacy of Immunogenic Chemotherapeutics in Breast Cancer
-
Gao J, Deng F, Jia W
- KMID: 2450115
- J Breast Cancer.
- 2019 Jun;22(2):196-209.
- doi: 10.4048/jbc.2019.22.e23
PURPOSE: Breast cancer has become a major public health threat in the current society. Anthracycline doxorubicin (DOX) is a widely used drug in breast cancer chemotherapy. We aimed to investigate... -
- CITED
-
- Close
- SHARE
-
- Close
- Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study
-
Burr RL, Gu H, Cain K, Djukovic D, Zhang X, Han C, Callan N, Raftery D, Heitkemper M
- KMID: 2460485
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):551-562.
- doi: 10.5056/jnm19042
BACKGROUND/AIMS: Patients with irritable bowel syndrome (IBS) often report poor sleep quality. Whether poor sleep is associated with tryptophan (Trp) metabolites is unknown. We compared serum Trp metabolites in women... -
- CITED
-
- Close
- SHARE
-
- Close
