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Relationship between Autistic Spectrum Trait and Regional Cerebral Blood Flow in Healthy Male Subjects

Ota M, Matsuo J, Sato N, Teraishi T, Hori H, Hattori K, Kamio Y, Maikusa N, Matsuda H, Kunugi H

OBJECTIVE: Autistic spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development. The present study was carried out to investigate...
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A Single Intraperitoneal Injection of Endotoxin Changes Glial Cells in Rats as Revealed by Positron Emission Tomography Using [¹¹C]PK11195

Ota M, Ogura J, Ogawa S, Kato K, Matsuda H, Kunugi H

PURPOSE: Intracranial administration of lipopolysaccharide (LPS) is known to elicit a rapid innate immune response, activate glial cells in the brain, and induce depression-like behavior. However, no study has focused...
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Discrepancy between Clinician-rated and Self-reported Depression Severity is Associated with Adverse Childhood Experience, Autistic-like Traits, and Coping Styles in Mood Disorders

Yamada R, Fujii T, Hattori K, Hori H, Matsumura R, Kurashimo T, Ishihara N, Yoshida S, Sumiyoshi T, Kunugi H

Objective: This study aimed to determine if the discrepancy between depression severity rated by clinicians and that reported by patients depends on key behavioral/psychological features in patients with mood disorders. Methods:...
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