- Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes (Endocrinol Metab 2016;31:328-35, Cheol Ryong Ku et al.)
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Ku CR, Lee EJ
- KMID: 2352991
- Endocrinol Metab.
- 2016 Sep;31(3):482-483.
- doi: 10.3803/EnM.2016.31.3.482
No abstract available. -
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- The Characteristics and Follow-up of Pituitary Incidentaloma
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Ku CR, Lee EJ
- KMID: 2063560
- J Korean Endocr Soc.
- 2008 Apr;23(2):109-110.
- doi: 10.3803/jkes.2008.23.2.109
No abstract available. -
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- Early Prediction of Long-Term Response to Cabergoline in Patients with Macroprolactinomas
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Lee Y, Ku CR, Kim EH, Hong JW, Lee EJ, Kim SH
- KMID: 2169464
- Endocrinol Metab.
- 2014 Sep;29(3):280-292.
- doi: 10.3803/EnM.2014.29.3.280
BACKGROUND: Cabergoline is typically effective for treating prolactinomas; however, some patients display cabergoline resistance, and the early characteristics of these patients remain unclear. We analyzed early indicators predicting long-term response... -
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- Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine
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Kim K, Ku CR, Lee EJ
- KMID: 2546977
- Endocrinol Metab.
- 2023 Oct;38(5):463-471.
- doi: 10.3803/EnM.2023.1820
The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and... -
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- Characteristics of Acromegaly in Korea with a Literature Review
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Hong JW, Ku CR, Kim SH, Lee EJ
- KMID: 1973819
- Endocrinol Metab.
- 2013 Sep;28(3):164-168.
- doi: 10.3803/EnM.2013.28.3.164
Acromegaly is a slowly progressive disease caused by excessive growth hormone (GH), which is related to a GH secreting pituitary tumor in most cases. Herein, we describe the epidemiology, clinical... -
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- Precision Therapy in Acromegaly Caused by Pituitary Tumors: How Close Is It to Reality?
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Ku CR, Melnikov V, Zhang Z, Lee EJ
- KMID: 2503251
- Endocrinol Metab.
- 2020 Jun;35(2):206-216.
- doi: 10.3803/EnM.2020.35.2.206
Acromegaly presents with an enigmatic range of symptoms and comorbidities caused by chronic and progressive growth hormone elevations, commonly due to endocrinologic hypersecretion from a pituitary gland tumor. Comprehensive national... -
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- Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma with Ectopic Cushing's Syndrome
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Chung YS, Na M, Ku CR, Kim SH, Kim EH
- KMID: 2470923
- Yonsei Med J.
- 2020 Mar;61(3):257-261.
- doi: 10.3349/ymj.2020.61.3.257
Esthesioneuroblastoma as a source of ectopic Cushing's syndrome is rare, and to the best of our knowledge, only 20 cases have been reported worldwide. A 46-year-old healthy man visited a... -
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- A Case of Unilateral Renal Artery Stenosis with Contra-Lateral Focal Segmental Glomerulosclerosis in a Chronic Kidney Disease Patient
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Hong SJ, Kim DK, Ku CR, Lee HS, Choi KH, Lee HY, Han DS, Jeong HJ, Kim BS
- KMID: 2254054
- Korean J Nephrol.
- 2007 Mar;26(2):264-268.
We report a case of focal segmental glomerulosclerosis (FSGS) with chronic renal failure in a patient with unilateral renal artery stenosis. A 38-year-old woman presented with malignant hypertension, massive proteinuria... -
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- A Case of Graves' Disease Presenting with Chorea
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Ku CR, Park HJ, Hong SJ, Shin DY, Lee JH, Chung MJ, Cho MA, Noh TW, Lee BI, Lee EJ
- KMID: 1479228
- J Korean Endocr Soc.
- 2008 Oct;23(5):342-346.
- doi: 10.3803/jkes.2008.23.5.342
Hyperthyroidism is invariably accompanied by nervous system dysfunction. Specifically, irritability, emotional lability, and hyperkinesia are the signs and symptoms most frequently observed. In rare instances, chorea and/or choreoathetosis are associated... -
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- Establishment of Reference Intervals for Serum Insulin-Like Growth Factor I in Korean Adult Population
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Kim B, Cho Y, Ku CR, Lee SG, Lee KA, Kim JH
- KMID: 2511024
- Endocrinol Metab.
- 2020 Dec;35(4):960-964.
- doi: 10.3803/EnM.2020.732
Appropriate reference intervals of serum insulin-like growth factor I (IGF-I) is important for diagnosing and monitoring patients with growth hormone-related diseases. To establish reference intervals, adult individuals (n=1,334, 680 men... -
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- Surgical Treatment of Prolactinomas: Potential Role as a First-Line Treatment Modality
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Kim EH, Kim J, Ku CR, Lee EJ, Kim SH
- KMID: 2544917
- Yonsei Med J.
- 2023 Aug;64(8):489-496.
- doi: 10.3349/ymj.2022.0406
Purpose: Treatment with dopamine agonists (DAs) has been the first-line standard treatment for prolactinoma, and surgery has been reserved for drug intolerance and resistance for several decades. We evaluated whether... -
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- A Case of X-Linked Agammaglobulinemia with Btk Gene Intron 2 Mutation
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Chung MJ, Jung JY, Son JY, Ku CR, Park BH, Byun MK, Moon JA, Kim YS, Kim SK, Chang J, Kim SK, Shin DM, Park MS
- KMID: 2319075
- Tuberc Respir Dis.
- 2008 Sep;65(3):207-211.
X-linked agammaglobulinemia is the most common type of primary immunodeficiency disorder. Mutation ofthe cytoplasmic tyrosine kinase gene, Btk (Bruton's tyrosine kinase), is known to be the etiology of X-linked agammaglobulinemia.... -
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- Spontaneous Non-Traumatic Stress Fractures in Bilateral Femoral Shafts in a Patient Treated with Bisphosphonates
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Shin DY, Ku CR, Kim KM, Choi HS, Rhee Y, Lee EJ, Lim SK
- KMID: 1776573
- Korean J Intern Med.
- 2012 Mar;27(1):98-102.
- doi: 10.3904/kjim.2012.27.1.98
Bisphosphonates are potent inhibitors of bone resorption and widely used to treat osteoporosis. Extensive studies have shown that therapy with bisphosphonates improves bone density and decreases fracture risk. However, concerns... -
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- Danshen Extracts Prevents Obesity and Activates Mitochondrial Function in Brown Adipose Tissue
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Cho YH, Ku CR, Choi YS, Lee HJ, Lee EJ
- KMID: 2513301
- Endocrinol Metab.
- 2021 Feb;36(1):185-195.
- doi: 10.3803/EnM.2020.835
Background: Danshen has been widely used in oriental medicine to improve body function. The purpose of this study is to investigate the effect of water-soluble Danshen extract (DE) on weight... -
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- A Case of Pituitary Adenoma with Simultaneous Secretion of TSH and GH
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Lee EY, Ku CR, Kim HM, Lee WK, Lim JS, Hwang S, Kim DH, Shin DY, Lee EJ
- KMID: 1497724
- Endocrinol Metab.
- 2011 Jun;26(2):160-165.
- doi: 10.3803/EnM.2011.26.2.160
Thyrotropin (TSH)-secreting pituitary adenoma is a very rare disease. In one-quarter of patients suffering from this disease, the pituitary tumor secretes other anterior pituitary hormones. Herein, we report a case... -
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- Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea
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Kim J, Hong N, Choi J, Moon JH, Kim EH, Lee EJ, Kim SG, Ku CR
- KMID: 2549262
- Endocrinol Metab.
- 2023 Dec;38(6):690-700.
- doi: 10.3803/EnM.2023.1782
Background: Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean... -
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- The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes
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Ku CR, Cho YH, Hong ZY, Lee H, Lee SJ, Hong SS, Lee EJ
- KMID: 2308864
- Endocrinol Metab.
- 2016 Jun;31(2):328-335.
- doi: 10.3803/EnM.2016.31.2.328
BACKGROUND: Resveratrol (RSV) is a polyphenolic phytoalexin that has many effects on metabolic diseases such as diabetes and obesity. Given the importance of brown adipose tissue (BAT) for energy expenditure,... -
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- Associations of GNAS Mutations with Surgical Outcomes in Patients with Growth Hormone-Secreting Pituitary Adenoma
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Jung H, Kim K, Kim D, Moon JH, Kim EH, Kim SH, Ku CR, Lee EJ
- KMID: 2515460
- Endocrinol Metab.
- 2021 Apr;36(2):342-350.
- doi: 10.3803/EnM.2020.875
Background: The guanine nucleotide-binding protein, alpha stimulating (GNAS) gene has been associated with growth hormone (GH)-secreting pituitary adenoma. We investigated the prevalence of GNAS mutations in Korean patients with acromegaly... -
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- Clinical Significance of Radical Surgery in the Treatment of Silent Corticotroph Adenoma
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Kim J, Yoon SJ, Moon JH, Ku CR, Kim SH, Lee EJ, Kim SH, Kim EH
- KMID: 2434353
- J Korean Neurosurg Soc.
- 2019 Jan;62(1):114-122.
- doi: 10.3340/jkns.2018.0027
OBJECTIVE: Silent corticotroph adenomas (SCA) are endocrine-inactive pituitary adenomas with positive immunohistochemistry staining for adrenocorticotropic hormone (ACTH). We investigated whether SCA-associated clinical profiles were more aggressive than hormonally negative adenomas... -
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- Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas
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Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ
- KMID: 2471734
- Endocrinol Metab.
- 2020 Mar;35(1):177-187.
- doi: 10.3803/EnM.2020.35.1.177
BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing... -
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