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Regional Gastrointestinal Transit Times in Patients With Carcinoid Diarrhea: Assessment With the Novel 3D-Transit System

Gregersen , Haase AM, Schlageter V, Gronbaek H, Krogh K

  • KMID: 2433482
  • J Neurogastroenterol Motil.
  • 2015 Jul;21(3):423-432.
  • doi: 10.5056/jnm15035
BACKGROUND/AIMS: The paucity of knowledge regarding gastrointestinal motility in patients with neuroendocrine tumors and carcinoid diarrhea restricts targeted treatment. 3D-Transit is a novel, minimally invasive, ambulatory method for description of...
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Rectal Mechano-sensory Function in Patients with Carcinoid Diarrhea

Gregersen , Brock C, Haase AM, Laurberg S, Drewes AM, Grønbæk , Krogh K

  • KMID: 2203580
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):264-271.
  • doi: 10.5056/jnm15113
BACKGROUND/AIMS: In patients with neuroendocrine tumors, excessive production of serotonin and other amines may cause the carcinoid syndrome, which is mainly characterized by diarrhea and flushing. Little is known about...
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The Impact of Opioid Treatment on Regional Gastrointestinal Transit

Poulsen JL, Nilsson M, Brock C, Sandberg T, Krogh K, Drewes AM

  • KMID: 2203582
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):282-291.
  • doi: 10.5056/jnm15175
BACKGROUND/AIMS: To employ an experimental model of opioid-induced bowel dysfunction in healthy human volunteers, and evaluate the impact of opioid treatment compared to placebo on gastrointestinal (GI) symptoms and motility...
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Early Assessment of Cost-effectiveness of Gastric Electrical Stimulation for Diabetic Nausea and Vomiting

Klinge MW, Rask P, Mortensen , Lassen K, Ejskjaer N, Ehlers LH, Krogh K

  • KMID: 2395422
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):541-549.
  • doi: 10.5056/jnm16179
BACKGROUND/AIMS: Recurrent nausea and/or vomiting are common complications of diabetes mellitus. The conditions severely impact the quality of life of patients and often cause repeated admissions to hospital incurring significant...
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Effects of Naloxegol on Gastrointestinal Transit and Colonic Fecal Volume in Healthy Participants Receiving Oxycodone

Olesen AE, Grønlund , Mark EB, Krogh K, Frøkjær , Drewes AM

  • KMID: 2460489
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):602-610.
  • doi: 10.5056/jnm18079
BACKGROUND/AIMS: Opioids cause gastrointestinal (GI) dysmotility, decrease gut secretion, and affect gut sphincters. Symptoms of opioid-induced bowel dysfunction may be alleviated by peripherally acting opioid antagonists like naloxegol, but detailed...
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Gastric Emptying Time and Volume of the Small Intestine as Objective Markers in Patients With Symptoms of Diabetic Enteropathy

Klinge MW, Sutter N, Mark EB, Haase AM, Borghammer P, Schlageter V, Lund S, Fleischer J, Knudsen K, Drewes AM, Krogh K

  • KMID: 2517533
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):390-399.
  • doi: 10.5056/jnm19195
Background/Aims Patients with diabetes mellitus (DM) often suffer from gastrointestinal (GI) symptoms, but these correlate poorly to established objective GI motility measures. Our aim is to perform a detailed evaluation of...
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Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350

Poulsen JL, Mark EB, Brock C, Frøkjær , Krogh K, Drewes AM

  • KMID: 2417279
  • J Neurogastroenterol Motil.
  • 2018 Jan;24(1):119-127.
  • doi: 10.5056/jnm17058
BACKGROUND/AIMS: Opioid-induced constipation (OIC) is the most common gastrointestinal (GI) side effect to opioid treatment. Opioid receptor antagonists against OIC have been introduced, but their efficacy has not been directly...
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Axial Movements and Length Changes of the Human Lower Esophageal Sphincter During Respiration and Distension-induced Secondary Peristalsis Using Functional Luminal Imaging Probe

Liao D, Lottrup C, Fynne L, McMahon BP, Krogh K, Drewes AM, Zhao J, Gregersen

  • KMID: 2413102
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):255-267.
  • doi: 10.5056/jnm17084
BACKGROUND/AIMS: Efficient transport through the esophago-gastric junction (EGJ) requires synchronized circular and longitudinal muscle contraction of the esophagus including relaxation of the lower esophageal sphincter (LES). However, there is a...
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