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pncA Mutations in the Specimens from Extrapulmonary Tuberculosis

Lee J, Yun YJ, Kqueen CY, Lee JH, Kim HY, Kim YR, Kook YH, Lee KH

  • KMID: 2319847
  • Tuberc Respir Dis.
  • 2012 Jun;72(6):475-480.
BACKGROUND: Pyrazinamide (PZA) is an effective antitubercular drug that becomes toxic to Mycobacterium tuberculosis when converted to pyrazinoic acid by pyrazinamidase (PZase), encoded by mycobacterial pncA. A strong association was...
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