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Loss-of-function mutation in Pcsk1 increases serum APOA1 level and LCAT activity in mice

Khan AA, Kim N, Korstanje R, Choi S

Background: The convertase subtilisin/kexin family 1 gene (PCSK1) has been associated in various human genetics studies with a wide spectrum of metabolic phenotypes, including early-onset obesity, hyperphagia, diabetes insipidus, and...
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