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Acute Pancreatitis Associated with Olanzapine: A Case Report

Kang SH, Kim CY

  • KMID: 2286988
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):485-487.
Olanzapine is a thienobenzodiazepine similar in structure to clozapine. Several case reports have suggested that clozapine and olanzapine may be associated with the induction of acute pancreatitis. We present a...
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Past, Present and Future of Dopamine Hypothesis for Schizophrenia

Chung YC, Li CR

  • KMID: 2286977
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):393-400.
Many neurotransmitters other than dopamine, such as serotonin, glutamate, etc, have been implicated in the pathophysiology of schizophrenia. The atypicality of new antipsychotics has been attributed to the relatively more...
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The Rationale and Effect of Antipsychotics Combination Therapy

Lee Y

  • KMID: 2286978
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):401-414.
Up to the present date, the principle of antipsychotics treatment in patients with schizophrenia is antipsychotics monotherapy. The reasons for the drug monotherapy may be associated with the fact that...
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A Case of Restless Leg Syndrome Induced by Mirtazapine in a Patient with Major Depressive Disorder

Jung HY, Lee SI, Kim DH, Choi EJ

  • KMID: 2286989
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):488-491.
Mirtazapine is a novel antidepressant and has a unique dual action profile, combining the enhancement of the noradrenergic neurotransmitter system with specific actions on particular serotonergic receptor subtypes. The authors...
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A Case of Agranulocytosis Induced by Olanzapine and Treated with Granulocyte-Colony Stimulating Factor

Lee WH, Kim W, Chae JH, Jun TY, Bahk WM

  • KMID: 2286987
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):480-484.
Agranulocytosis is a severe hematologic complication of clozapine, but olanzapine was not shown to induce agranulocytois. Nevertheless, some cases of olanzapine-induced agranulocytosis have been reported, but there was no report...
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Fluoxetine-induced Changes on Activity of Tryptophan Hydroxylase at RBL-2H3 Cells

Baik SY, Jung KH, Choi MR, Yang BH, Kim SH, Choi IG, Chai YG

  • KMID: 2286983
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):449-456.
OBJECTIVES: The aim of the present study is to explore the effect of fluoxetine on transcription, translation and activity of tryptophan hydroxylase (TPH), and intracellular level of serotonin. METHODS: The...
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Effect of Pharmacotherapy with Paroxetine on Biofeedback Measurement Variables in Panic Disorder Patients

Ryu HW, Koo MS, Yu BH

  • KMID: 2286985
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):468-473.
OBJECTIVE: There have been much effort to find reliable indicators predicting treatment response in panic disorder. This study aimed to find the effect of pharmacotherapy on biofeedback measurement variables in...
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Dysregulation of Cell Cycle Regulating Proteins in Peripheral Lymphocytes from the Patients with Alzheimer's Disease

Chung SH, Kwon YA, Kim H, Shin JY, Kim DK

  • KMID: 2286986
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):474-479.
OBJECTIVE: Extensive neuronal death occurring in the Alzheimer's disease (AD) may be related with the apoptosis. Recent studies have suggested that regulatory failure of cell cycle appeared to be very...
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CREB Expression in Peripheral Lymphocyte and Antidepressant Response

Shin JY, Lim SW, Chung SH, Kim H, Kim DK

  • KMID: 2286982
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):440-448.
OBJECTIVE: The molecules related with the intracellular signal transduction system are one of the main targets for the mode of mechanisms of antidepressant treatment in depressive patients. In vivo and...
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Characterization of Differentially Expressed Genes upon Chronic Fluoxetine Treatment in Rat C6 Glioma Cells

Choi MR, Baik SY, Jung KH, Chai YG, Kim SH, Roh S, Lee JS, Oh DY, Choi IG, Yang BH

  • KMID: 2286984
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):457-467.
OBJECTIVE: The aim of this study was to identify diffrentially regulated genes after the treatment of fluoxetine in rat C6 glioma cells using cDNA microarray chip techniques and real-time RT-PCR....
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A Clinical Trial of Topiramate for Weight Loss in Schizophrenia with Overweight or Obesity

Ko YH, Joe SH, Do SY, Cho W, Park JH, Chun DY, Kim KT, Woo GS, Kwon SM

  • KMID: 2286981
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):433-439.
OBJECTIVE: Antipsychotic-induced weight gain is associated with treatment noncompliance and is also known to be associated with several medical conditions in schizophrenia. Topiramate, a relatively new antiepileptic drug, is currently...
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Effectiveness and Tolerability of Topiramate Versus Divalproex in Bipolar Mania

Bahk WM, Shin YC, Woo JM, Yoon BH, Lee JS, Jon DI, Chung SK, Paik IH, Pae CU

  • KMID: 2286980
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):425-432.
Mood stabilizers and atypical antipsychotics are commonly combined for the treatment of bipolar mania. The aim of this study was to compare the effectiveness and tolerability of topiramate and divalproex...
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The Patterns of Antipsychotic Drug Use in Schizophrenic Patients Registered at the Day Rehabilitation Programs of Mental Health Centers

Chung IW, Suh T, Son JW, Lee YK

  • KMID: 2286979
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):415-424.
OBJECTIVE: This study was to explore the use patterns of antipsychotic drugs in schizophrenic patients who registered at the day rehabilitation programs in mental health centers. METHODS: The sociodemographic and...
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