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Efficacy of Clozapine on Schizophrenia with Polydipsia: Two Cases Experience

Kim CE, Park NJ, Kang MH, Bae JN

  • KMID: 2287348
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):63-66.
Polydipsia occurs frequently in chronic schizophrenic patients, some of whom develop hyponatremia. Although the underlying pathophysiology of polydipsia among psychiatric patients, recent reports indicate that clozapine treatment improves polydipsia-hyponatremia in...
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Stereoisomerism(Chirality) of Psychotropic Drugs

Chung IW

  • KMID: 2287341
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):3-10.
Many psychotropic drugs are marketed and prescribed as a racemate form in a mixture of the stereoisomers. A chiral center or a center of unsaturation of carbon atoms in the...
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Differential Changes in Neural Activity of Prefrontal Cortical Neurons of Behaving Rats by Clozapine Administration

Ha HJ, Jung MW, Han SJ, Chung YK

  • KMID: 2287344
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):28-34.
OBJECTIVE: A previous study indicated that acute treatment of clozapine increased the neural activity of prefrontal cortical neurons of anesthetized rats. This study was to investigate the effect of clozapine...
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Treatment Strategy for Antidepressant-Resistant Depression in Korea: A Survey of Clinicians

Jung HY, Lee SI, Kim JK, Park JH

  • KMID: 2287346
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):40-47.
OBJECTIVE: This survey was conducted to examine psychiatrists' next-step strategies in depressed patients, when failed to respond to an adequate trial of SSRIs. METHODS: We asked 200 Korean psychiatrists who...
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Risperodone Induced Hyperprolactinemia and Its Clinical Complications

Park N, Bae J, Kang M, Kim C

  • KMID: 2287345
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):35-39.
OBJECT: Risperidone, unlike other atypical antipsychotics, is thought to elevate prolactin levels. This paper examines the relationship of risperidone-induced hyperprolactinemia and the sexual dysfunctions of the patients in the real...
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Effect of Amantadine on Weight Gain Induced by Olanzapine

Bahk WM, Lee KU, Chae JH, Lee WH, Jun T, Kim KS

  • KMID: 2287343
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):23-27.
OBJECTIVE: Weight gain is a commonly encountered problem associated with atypical antipsychotics, especially olanzapine. To investigate the weight reducing effect of amantadine, we conducted an prospective open label study. METHODS:...
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Bipolar Spectrum Disorder

Choi EJ, Jung HY, Lee SY

  • KMID: 2287342
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):11-22.
The concept of bipolar disorder is an ongoing process, still in evolution, although its roots can be found from ancient Greek. Until recently, it was believed that no more than...
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The Effects of Olanzapine in the Treatment of Inpatients with Schizophrenia and Other Psychotic Disorders: Efficacy, Safety and Quality of Life

Shin IS, Kim JM, Kim DI, Kim SH, Kim JH, Shin MS, Jung YC, Jung IW, Chee IS, Yoon BH, Yoon JS

  • KMID: 2287347
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):48-62.
OBJECTIVE: This multicenter, open trial with olanzapine was primarily designed to evaluate effects of olanzapine on profiles of efficacy, safety, and subjective quality of life (QoL) in hospitalized patients with...
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