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Pharmacogenomics of Antipsychotic Drugs

Kim CY, Joo YH

  • KMID: 1985325
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):85-94.
There is a substantial variation in the treatment response and adverse reactions to antipsychotic drugs. Pharmacogenomics of antipsychotic drugs is to identify the gene(s) related with this variability in outcome...
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Pharmacogenomics of Antidepressants

Han CS, Kim SH

  • KMID: 1985324
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):75-84.
In an approach known as pharmacogenomics, many psychopharmacologists hope to match depressive patients to specific drugs based on the patients' genetic profiles. Many researchers and pharmaceutical companies are investing their...
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Clinical Experience of Clozapine Discontinuation: Comparison between Sulpiride and Thioridazine Switch Group

Lee HS, Koo MS, Cho HS, Park IH, Kim CH

  • KMID: 1985327
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):104-112.
OBJECTIVE: Several reports have found that withdrawal symptoms of clozapine are more severe and common than that of the typical antipsychotics. The objective of this study was to report the...
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Effects of Nitric Oxide Synthase (NOS) Inhibitor on MIL801-elicited Behaviors in Rats

Suh KW, Baek SY, Chung YI

  • KMID: 1985328
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):113-119.
OBJECTIVE: The aim of the present study was to investigate the effects of nitric oxide synthase (NOS) inhibitor on MK-801-elicited behaviors in rats in an attempt to elucidate the participation...
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Dopamine Transporter Density of the Basal Ganglia in Children with Attention Deficit Hyperactivity Disorder Assessed with I-123 IPT SPECT

Cheon KA, Ryu YH, Kim YK, Namkoong K, Kim CH

  • KMID: 1985326
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):95-103.
OBJECTIVE: ADHD has been known as a psychiatric disorder in childhood associated with dopamine dysregulation. In the present study, we investigated dopamine transporter (DAT) density using I-123N-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane (I-123-IPT)-SPECT in...
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Prevalence of Hyperlipidemia & Hyperglycemia Associated with Antipsychotics: Preliminary Study

Kim HS, Kim SJ

  • KMID: 1985329
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):120-130.
OBJECTIVE: Weight gain and DM can be serious side effects in the use of atypical antipsychotics (AAP), although conventional antipsychotics (CAP) have also been implicated. Also weight gain & DM...
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