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There is a substantial variation in the treatment response and adverse reactions to antipsychotic drugs. Pharmacogenomics of antipsychotic drugs is to identify the gene(s) related with this variability in outcome...
In an approach known as pharmacogenomics, many psychopharmacologists hope to match depressive patients to specific drugs based on the patients' genetic profiles. Many researchers and pharmaceutical companies are investing their...
OBJECTIVE: Several reports have found that withdrawal symptoms of clozapine are more severe and common than that of the typical antipsychotics. The objective of this study was to report the...
OBJECTIVE: The aim of the present study was to investigate the effects of nitric oxide synthase (NOS) inhibitor on MK-801-elicited behaviors in rats in an attempt to elucidate the participation...
OBJECTIVE: ADHD has been known as a psychiatric disorder in childhood associated with dopamine dysregulation. In the present study, we investigated dopamine transporter (DAT) density using I-123N-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane (I-123-IPT)-SPECT in...
OBJECTIVE: Weight gain and DM can be serious side effects in the use of atypical antipsychotics (AAP), although conventional antipsychotics (CAP) have also been implicated. Also weight gain & DM...