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A Case of Risperidone-Induced Stuttering

Lee HJ, Kwak DI

  • KMID: 1554208
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):196-198.
Stuttering as a side effect of antipsychotics is rare. There are only 4 reports of neuroleptic-induced stuttering. Most reports of neuroleptic-inducted stuttering involved low-potency drugs that have high intrinsic antimuscarinic...
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Plasma Serotonin Level in Posttraumatic Stress Disorder

Choi HS, Kang HS, Choi JH

  • KMID: 1554200
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):143-149.
OBJECTIVE: This research was performed to investigate whether or not the pathophysiology of posttraumatic stress disorder may be related to serotonin system. METHOD: Plasma serotonin levels were measured in 23...
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A Case of Clozapine-Induced Eosinophilia Combined with Bilateral Pleural Effusion, Ascites, Cholecysctitis, and Hepatitis

Hong HJ, Kim CH, Song DH, Lee SJ, Lee HS

  • KMID: 1554207
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):191-195.
Several blood dyscrasias associated with clozapine have been well known to clinicians and potentially life threatening agranulocytosis has been widely reported. However, there is little report regarding incidence, progression and...
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Animal Models of Schizophrenia

Chung YC

  • KMID: 1554196
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):109-119.
Animal models of schizophrenia and the mechanisms of symptom-formation based on the study of those were reviewed. Firstly, in the animal models of schizophrenia, there are three subtypes: genetic, homologous,...
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Agranulocytosis and Neutropenia in Clozapine-Treated Patients

Cho HS, An SK, Kim CH, Lee HS

  • KMID: 1554203
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):166-172.
OBJECTIVE: Clozapine is effective in the treatment of refractory schizophrenic patients, but can cause reversible and fatal food dyscrasias. This study documents the incidence of agranulocytosis and neutropenia and the...
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Does 3-O-Methyldopa(3-OMD) Inhibit the Binding of Levodopa to Plasma Protein

Bae JW, Harder S

  • KMID: 1554205
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):180-184.
OBJECTIVE: We determined the influence of 3-OMD in the protein binding of levodopa to estimate the effect of 3-OMD on the penetration of levodopa into brain. METHOD: P-glycoprotein in the brain...
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Folate Augmentation Therapy in Depression

Yoon CH

  • KMID: 1554206
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):185-190.
OBJECTIVE: It has been suggested that folate deficiency can cause psychiatric disturbances of depressive nature and the possible pathogenetic mediating mechanism is the deflect in methylation processes of S-adenosylmethionine in...
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Relationship between Serum Lipids and Psychiatric Symptoms

Hong HJ, Min SK, Koh KB, Kim JH

  • KMID: 1554197
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):120-129.
OBJECT: Many studies found that psychological stress produced significant increases in cholesterol concentration. But recent study results suggested that lowering cholesterol increased non-illness mortality. Suicide rate were higher in low...
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Effect of Ritanserin on the Circling Movement in the Unilateral Substantia Nigra-Lesioned Rats

Kim IH, Chung YC, Eun HB

  • KMID: 1554198
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):130-137.
OBJECTIVE: Recently, the serotonin-dopamine interaction is being regarded as a possible mechanism for both less extrapyramidal symptoms and good therapeutic effect on negative symptoms which are outstanding advantages of atypical...
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Guidelines for the Adequate Initial Electric Stimuli in Bilateral ECT Using MECTA Device

Lee MB, Ahn JH, Lee C, Han OS, Kim CY

  • KMID: 1554199
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):138-142.
OBJECTIVE: In applying Electro-Convulsive Therapy(ECT) to patients, initial electric stimuli have been often determined without the adequate guidelines. This study was designed to determine adequate numerical value of parameters for...
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Effect of Tetrahydro-9-Aminoacridine on Acetylcholine Release in the Rat Hippocampus

Joo YH, Kim SW, Rho SH, Choi BK

  • KMID: 1554204
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):173-179.
It is well known that the cholinergic innervation of hippocampal formation plays an important role in the process of memory and learning, and the deficit of this system might be...
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Effects of Selective Serotonin Reuptake Inhibitors(SSRIs) on Serotonin-mediated Intracellular Ca2+ Mobilization in Human Platelets

Han JK, Park KC, Kim HK, Lee JW

  • KMID: 1554201
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):150-157.
OBJECTIVE: The effects of treatment with selective serotonin reuptake inhibitors (SSRIs) on serotonin (5-HT)-mediated Ca(2+) mobilization were investigated in the platelets of human healthy volunteers. METHOD: The serotonin (5-HT)-mediated Ca(2+) mobilization...
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Changes in Serum Prolactin Levels after the Administration of Risperidone in Schizophrenic Patients: Gender Difference

Kim KS, Sung YS, Chae JH, Bahk WM, Lee CT, Lew TY

  • KMID: 1554202
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):158-165.
OBJECTIVE: In spite of being an atypical antipsychotic which has serotonergic(5HT2) biocking activity in addition to the dopaminergic(D2) antagonistic action, risperidone elevates serum prolactin level. Hyperprolactinemia secondary to neuroleptic treatment...
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