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Enhanced detection and serotyping of Streptococcus pneumoniae using multiplex polymerase chain reaction

Ahn JG, Choi SY, Kim DS, Kim KH

PURPOSE: Methods for quick and reliable detection of Streptococcus pneumoniae are needed for the diagnosis of pneumococcal disease and vaccine studies. This study aimed to show that sequential multiplex polymerase...
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A case of Kikuchi-Fujimoto disease with autoimmune thyroiditis

Go EJ, Jung YJ, Han SB, Suh BK, Kang JH

Kikuchi-Fujimoto disease (KFD) is a benign self-limiting disease characterized by fever and lymphadenitis. The etiology and pathogenesis of KFD is unclear. However, two hypotheses have been suggested: a viral infection...
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Regional differences in phylogenetic group of Escherichia coli strains isolated from children with urinary tract infection in Korea

Choi UY, Han SB, Lee SY, Kang JH, Kim SM, Ma SH

PURPOSE: We phylogenetically analyzed the Escherichia coli strains isolated from children with urinary tract infection (UTI) in 2 regions of Korea. Virulence factors (VFs) and antibiotic resistance of the strains...
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Understanding noninferiority trials

Hahn S

Noninferiority trials test whether a new experimental treatment is not unacceptably less efficacious than an active control treatment already in use. With continuous improvements in health technologies, standard care, and...
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Early neurodevelopment in very low birth weight infants with mild intraventricular hemorrhage or those without intraventricular hemorrhage

Choi IR, Lee JH, Park MS, Kim JY, Park KH, Kim GH, Eun SH

PURPOSE: This study aimed to assess early development in very low birth weight (VLBW) infants with mild intraventricular hemorrhage (IVH) or those without IVH and to identify the perinatal morbidities...
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Indirect revascularization surgery for moyamoya disease in children and its special considerations

Wang KC, Phi JH, Lee JY, Kim SK, Cho BK

Moyamoya disease (MMD) is the most common pediatric cerebrovascular disease in Far Eastern countries. In children, MMD frequently manifests as ischemic symptomatology. Cerebral perfusion gradually decreases as the disease progresses,...
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Clinical, radiologic, and genetic features of Korean patients with Mucopolysaccharidosis IVA

Lee NH, Cho SY, Maeng SH, Jeon TY, Sohn YB, Kim SJ, Park HD, Jin DK

PURPOSE: Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is rare lysosomal storage disorder caused by N-acetylgalactosamine-6-sulfatase (GALNS) deficiency. Only a few MPS IVA cases have been reported in the Korean...
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A case of mucolipidosis II presenting with prenatal skeletal dysplasia and severe secondary hyperparathyroidism at birth

Heo JS, Choi KY, Sohn SH, Kim C, Kim YJ, Shin SH, Lee JM, Lee J, Sohn JA, Lim BC, Lee JA, Choi CW, Kim EK, Kim HS, Kim BI, Choi JH

Mucolipidosis II (ML II) or inclusion cell disease (I-cell disease) is a rarely occurring autosomal recessive lysosomal enzyme-targeting disease. This disease is usually found to occur in individuals aged between...
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