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Genetics of kidney development: pathogenesis of renal anomalies

Hahn H

Congenital anomalies of the kidney and urinary tract (CAKUT) account for more than 50% of abdominal masses found in neonates and involve about 0.5% of all pregnancies. CAKUT has a...
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Renal fibrosis

Cho MH

Renal fibrosis, characterized by tubulointerstitial fibrosis and glomerulosclerosis, is the final manifestation of chronic kidney disease. Renal fibrosis is characterized by an excessive accumulation and deposition of extracellular matrix components....
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Secondary renal amyloidosis in a 13-year-old girl with bronchiectasis

Yang EA, Lee DW, Hyun MC, Cho MH

A 13-year-old girl was diagnosed with non-cystic fibrosis (CF)-related multifocal bronchiectasis accompanied by nephrotic-range proteinuria of unknown cause. On renal biopsy, there were many segmental homogeneous deposits of amyloid tissue...
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A case of Pfeiffer syndrome with c833_834GC>TG (Cys278Leu) mutation in the FGFR2 gene

Lee MY, Jeon GW, Jung JM, Sin JB

Pfeiffer syndrome is a rare autosomal dominant disorder characterized by coronal craniosynostosis, brachycephaly, mid-facial hypoplasia, and broad and deviated thumbs and great toes. Pfeiffer syndrome occurs in approximately 1:100,000 live...
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Effect of p16 on glucocorticoid response in a B-cell lymphoblast cell line

Kim SY, Lee KY, Jeong DC, Kim HK

PURPOSE: It has been suggested that p16 has a role in glucocorticoid (GC)-related apoptosis in leukemic cells, but the exact mechanisms have yet to be clarified. We evaluated the relationship...
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Clinical outcome of acute myocarditis in children according to treatment modalities

Kim HJ, Yoo GH, Kil HR

PURPOSE: There is currently little evidence to support intravenous immune globulin (IVIG) therapy for pediatric myocarditis. The purpose of our retrospective study was to assess the effects of IVIG therapy...
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Long-term safety of PEG 4000 in children with chronic functional constipation: A biochemical perspective

Bae SH

PURPOSE: To evaluate the long-term safety of polyethylene glycol (PEG) 4000 in children with constipation, particularly the biochemical aspects of safety. METHODS: Medical records were evaluated, and 100 children, who had...
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Risk factor for pituitary dysfunction in children and adolescents with Rathke's cleft cysts

Lim HH, Yang SW

PURPOSE: This study evaluated the clinical manifestations of and risk factors for pituitary insufficiency in children and adolescents with Rathke's cleft cysts. METHODS: Forty-four patients with Rathke's cleft cysts younger than...
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A case of regression of atypical dense deposit disease without C3 deposition in a child

Kim MS, Hwang PH, Kang MJ, Lee DY

Dense deposit disease (DDD) is a rare disorder characterized by the deposition of abnormal electron-dense material within the glomerular basement membrane of the kidneys. The diagnosis is made in most...
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