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Spindle Cell/Pleomorphic Lipoma of the Oropharynx

Gu MJ, Sohn KR, Park JH

We report a rare case of spindle cell/pleomorphic lipoma of the oropharynx. A 45-year-old woman presented with a 9-month history of a lump in 2001. A well demarcated polypoid, rubbery...
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Cytologic Features of Diffuse Sclerosing Variant of Papillary Carcinoma: Cytohistopathologic Analysis of 16 Cases

Koo JS, Jung W, Hong S, Yim H

BACKGROUND: The exact preoperative diagnosis of diffuse sclerosing papillary carcinoma (DSPC) is required for aggressive surgical treatment due to its extended involvement with thyroid and neck lymph nodes. The present...
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Cytology of Follicular Dendritic Cell Sarcoma on Intraoperative Touch Imprint Smears: A Case Report

Song JY, Jin XJ, Han JY, Kim L, Park IS, Kim JM, Chu YC, Choi SJ

Follicular dendritic cell (FDC) sarcoma is a neoplastic proliferation of FDCs. Because its cytologic findings can vary widely, both the cytomorphology and histopathology of FDC sarcoma can impose a significant...
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Immunohistochemical and Molecular Characteristics of Follicular Patterned Thyroid Nodules with Incomplete Nuclear Features of Papillary Thyroid Carcinoma

Min HS, Choe G, Cho NY, Kang GH, Park SH, Park SY

BACKGROUND: Follicular patterned thyroid nodules with incomplete nuclear features of papillary thyroid carcinoma (FTN-INPTCs) are difficult to diagnose, and their biological behavior and association with follicular variants of PTC (FVPTCs)...
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A Case of Pancreatitis Presenting with Pancreatic Panniculitis: A Case Report

Kim SH, Chang SH, Park HJ

Pancreatic panniculitis is a rare disease in which necrosis of fat in the panniculus and other distant foci occur in the setting of pancreatic disease. The most common pancreatic disorders...
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Ovarian Endometrioid Adenocarcinoma with a Yolk Sac Tumor Component

Chung DH, Park S, Kyung HE, Kim NR, Ha SY, Lim S, Cho HY

Ovarian endometrioid adenocarcinoma (EAC) with a yolk sac tumor (YST) component is extremely rare. Only twelve cases have been reported in the English literature. We report here two additional cases...
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Hepatoid Thymic Carcinoma: A Case Report

Lee JH, Kim H, Chae YS, Won NH, Choi JS, Kim CH

We report here on a rare case of hepatoid thymic carcinoma in a 34-year-old man. The patient complained of a high fever and headache, and a 6.6cm-sized anterior mediastinal mass...
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Expression of E-cadherin and beta-catenin is Altered at Tumor Budding Sites, Whose Number is Associated with the Progression of Colorectal Carcinoma

Jang TJ

BACKGROUND: Tumor budding is present in the stroma at the invasive margin of colorectal carcinomas (CRC). The disintegration of cell adhesion molecules is closely related to this process. This study...
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Fine Needle Aspiration Cytologic Features of Well-Differentiated Papillary Mesothelioma in the Pleura: A Case Report

Ryu HS, Jin MS, Choi HS, Baek H, Koh JS

Well-differentiated papillary mesothelioma (WDPM) is a rare subtype of malignant mesothelioma, which is considered to have low malignant potential. Because of its rare occurrence in the pleura, cytopathologists are not...
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KIT/PDGFRA Expression and Mutation in Testicular Seminoma and Ovarian Dysgerminoma

Choi SY, Suh KS, Kim YB, Lee HJ, Kim ES, Park MJ

BACKGROUND: KIT and PDGFRA are tyrosine kinase receptors. Stem cell factor/KIT-mediated signaling plays a role in normal spermatogenesis, and the alteration of KIT is important in the pathogenesis of seminomas/dysgerminomas...
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Characterization of Histopathological Features that Differentiate Hepatitis B Virus Infection from Acute Cellular Rejection

Song DE, Jung DH, Hwang S, Park BH, Yu E

BACKGROUND: Differentiation of viral hepatitis from acute cellular rejection (ACR) after liver transplantation can be difficult because of overlapping histological features. Here we investigated clinicopathologic characteristics of 311 liver allograft...
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Myopathy due to Chronic Clevudine Therapy: A Case Report

Kim JY, Yoon YS, Park KD, Koo H

A 40-year-old man with chronic hepatitis B complained of progressive weakness of the proximal muscles and edema of both legs. He had been receiving long-term clevudine (nucleoside analogue reverse transcriptase...
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Alteration of G1/S Cell Cycle Regulatory Proteins in Carcinogenesis of Cutaneous Squamous Cell Carcinomas

Im S, Yoo C, Jung JH, Choi HJ, Yoo J, Kang SJ, Lee KY

BACKGROUND: Aberration of the cell cycle regulatory proteins has been reported to contribute to the development and progression of human malignancy. We studied the expression of G1/S cell cycle regulatory...
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Comparison of Liqui-PREP(TM) and Conventional Preparations in Thyroid Fine Needle Aspiration

Park ES, Cho EY, Do IG, Kim SJ, Shin JH, Han BK, Oh YL

BACKGROUND: Liqui-PREP(TM) (LP) is a new liquid-based cytologic preparation that produces a thin layer of cells. METHODS: Thyroid aspirates were obtained from 189 patients and divided to prepare pairs of...
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Intron 1 Polymorphism, Mutation and the Protein Expression of Epidermal Growth Factor Receptor in Relation to the Gefitinib Sensitivity of Korean Lung Cancer Patients

Kim MJ, Shin KC, Lee KH

BACKGROUND: Epidermal growth factor receptor (EGFR) intron 1 polymorphism in non-small cell lung cancer (NSCLC) has been found to have therapeutic implications for the patients treated with EGFR tyrosine kinase...
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Transcriptional Regulation of Hepatic Stellate Cell Activation by siRNA for TGF-beta1

Oh HK, Kim KH, Keum YS, Cho CH, Park JB, Park KK

BACKGROUND: The cytokine-induced activation of hepatic stellate cells (HSC) plays a major role in liver fibrosis. Quiescent HSCs undergo phenotypic transformation called "transdifferentiation" in response to viral, chemical or immune...
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Expression and Prognostic Significance of Serum Response Factor in Cholangiocarcinoma

Park SY, Jang KY, Kim YN, Kim HJ, Park HS, Chung MJ, Yu HC, Cho BH, Kim KR, Moon WS

BACKGROUND: Serum response factor (SRF) is a transcriptional factor that plays an important role in cell growth and differentiation for several types of cells. The expression of SRF in cholangiocarcinoma...
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