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Improved Technique of Digoxigenin Labeled RNA in situ Hybridization

Lee SK, Kim YS, Song IS, Lee SS, Lee YJ, Kim WH, Chi JG

  • KMID: 2275639
  • Korean J Pathol.
  • 2001 Apr;35(2):98-110.
BACKGROUND: A practical RNA in situ hybridization method using digoxigenin labeled RNA probes is described in order to evaluate the technical difficulties and problems in RNA in situ hybridization. METHODS:...
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Pulmonary Aspergillus niger Fungus Ball Associated with Calcium Oxalate Crystal: A Case Report

Lee E, Kim H, Chang E, Lee KY, Kim BK

  • KMID: 2275648
  • Korean J Pathol.
  • 2001 Apr;35(2):165-167.
Pulmonary aspergillomas are considered to represent saprophytic growth of hyphae within the preexisting lung cavity. Causative Aspergillus species are mostly composed of A. fumigatus and A. flavus and, occasionally, A....
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The Expression of Transforming Growth Factor-1 and Its Signaling Receptors in Human Colorectal Carcinoma

Kim GS, Kim JH, Moon WS, Chung MJ, Lee DG, Kang MJ

  • KMID: 2275641
  • Korean J Pathol.
  • 2001 Apr;35(2):115-122.
BACKGROUND: Resistance to the potent growth inhibitory effects of TGF- (transforming growth factor-) is a characteristic of many malignancies. TGF- insensitivity has been attributed to alterations in the number and...
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Expression of p16 and Rb in 9,10-Dimethyl-1,2-Benzanthracene Induced Rat Ovarian Carcinogenesis

Kim KK, Kim DH

  • KMID: 2275645
  • Korean J Pathol.
  • 2001 Apr;35(2):144-150.
BACKGROUND: In order to investigate the roles of p16 and Rb, their expression was evaluated in 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced ovarian cancers of rats. METHODS: DMBA-coated silk was inserted into both ovaries...
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Microsatellite Instability in Colorectal Carcinomas

Cha HJ, Woo DK, Kim SH, Kim YL, Park JG, Kim WH

  • KMID: 2275640
  • Korean J Pathol.
  • 2001 Apr;35(2):111-114.
BACKGROUND: Microsatellite instability (MSI), which is caused by a deficient mismatch repair system, is seen in most of the hereditary non-polyposis colon cancers and a portion of sporadic colorectal cancers....
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Pathological Analysis of 62 Liver Biopsy Cases with Hepatocellular Cholestasis: Drug and Toxin Induced Liver Injury

Cho MS, Park YN, Kim MJ, Chae KJ, Park C

  • KMID: 2275642
  • Korean J Pathol.
  • 2001 Apr;35(2):123-128.
BACKGROUND: Hepatocellular cholestasis denotes the alteration of bile secretion by hepatocytes. The causes, degree of hepatocyte injury and concomitant bile duct loss are considered to influence the clinical course. METHODS:...
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Atypical (Bizarre) Leiomyoma of the Prostate: A Case Report

Kim SR, Song SY, Ahn G, Choi HY

  • KMID: 2275650
  • Korean J Pathol.
  • 2001 Apr;35(2):172-175.
Atypical (bizarre) leiomyoma of the prostate is a very rare neoplasm. Five cases have been reported in English medical literature. A 60-year-old Korean man with a history of prostatism and...
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Ethnic Differences of the p53 Genetic Alteration in Cutaneous Malignant Melanoma

Park WS, Na EY, Lee SK, Lee SH, Kim SY, Kang SJ, Song KY, Nam SW, Yoo NJ, Lee JY

  • KMID: 2275647
  • Korean J Pathol.
  • 2001 Apr;35(2):158-164.
BACKGROUND: There are significant differences in the clincopathologic pattern including the incidence, favor site, and histopathologic type between cutaneous malignant melanomas arising from whites, asians and blacks. These differences might...
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Polyomavirus Renal Infection Confirmed by Electron Microscopy in a Patient with Acquired Immunodeficiency Syndrome: An Autopsy Case Report

Kim NR, Kim BK, Chi JG

  • KMID: 2275649
  • Korean J Pathol.
  • 2001 Apr;35(2):168-171.
Polyomavirus infection commonly occurs in childhood and adolescence, remaining in a latent status and reactivated in an immunocompromised status. We report herein an autopsy case of HIV-positive 41-year-old male, who...
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mRNA is Synthesized Mainly at the Phase between the Euchromatin and Heterochromatin: Proposal of a Phase Theory

Kim MS, Juhng SW

  • KMID: 2275638
  • Korean J Pathol.
  • 2001 Apr;35(2):93-97.
BACKGROUND: Malignant cell nuclei, in general, have increased amounts of heterochromatin and decreased electron densities of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. The...
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Expression of Cyclin D1, Cyclin E, p21Cip1 and p27Kip1 in Chemically Induced Rat Mammary Tumor Treated with Tamoxifen and Transforming Growth Factor-1

Jang TJ, Park JH, Cho MY, Kim KK, Kim JR

  • KMID: 2275646
  • Korean J Pathol.
  • 2001 Apr;35(2):151-157.
BACKGROUND: Tamoxifen (TAM) inhibits the action of estrogen by binding to estrogen receptors, and also has non-estrogen receptor mediated cytostatic activities. Transforming growth factor-1 (TGF-1) inhibits the proliferation of many...
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Study of Microsatellite Alterations of 3p and 11q Chromosomes in Uterine Cervical Adenocarcinoma

Lee ES, Jeong HJ, Kim HJ, Kim I

  • KMID: 2275644
  • Korean J Pathol.
  • 2001 Apr;35(2):137-143.
BACKGROUND: Uterine cervical cancer is the most prevalent cancer in Korean women, and the incidence of adenocarcinoma has been increasing. Loss of heterozygosity (LOH) analysis is used to identify regions...
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Choroid Plexus Carcinoma: A Report of Two Cases

Shim YR, Gu MJ, Kim DS, Kim OL, Byun WM, Kim YJ

  • KMID: 2275651
  • Korean J Pathol.
  • 2001 Apr;35(2):176-179.
Choroid plexus carcinoma (CPC), a frankly malignant epithelial neoplasm derived from choroid plexus epithelium, is a rare tumor with a predilection for infants and children. It may be difficult to...
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Metastatic Alveolar Soft Part Sarcoma Presented with a Dura Mass: A Case Report

Kwon SY, Joo HC, Kwon KY, Lee SS, Sohn CH, Yim MB, Kim SP

  • KMID: 2275652
  • Korean J Pathol.
  • 2001 Apr;35(2):180-183.
Alveolar soft part sarcoma, accounting for less than 1% of all soft tissue sarcomas, is known for late metastases to the lung, bone and brain. We have examined a case...
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A Study on the Expression of Proliferating Cell Nuclear Antigen and Apoptosis of the Hepatocellular Carcinoma in Human and Hepatitis B Virus X Transgenic Mice

Moon HB, Yu DY, Yoo HR, So BJ, Chae KM, Kim HC, Yun KJ, Han WC, Jo HJ, Kim BY

  • KMID: 2275643
  • Korean J Pathol.
  • 2001 Apr;35(2):129-136.
BACKGROUND: This experiment was designed to study the cell kinetics of hepatocellular carcinoma (HCC) in both hepatitis B virus X (HBx) transgenic mice and humans. METHODS: The immunohistochemical stain of...
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