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Development of Physiologically Based Pharmacokinetic Model for Several Volatile Organic Compounds

Jang JY, Lee KJ, Chung HK

  • KMID: 2141584
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):357-377.
Recently physiologically based pharmacokinetic (PB-PK) model has important role in industrial and environmental health. One of problem in application of PB-PK models is that they have uncertainties that is due...
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A Case of Occupational Asthma Associated with Chromium

Lim HS, Kim JY, Lee YH

  • KMID: 2141577
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):283-291.
Occupational asthma is an important occupation-related disease. We experienced a case of asthma induced by chromium. After discovery, chromium has been widely used in industry. Health effects of chromium and...
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Significance of Time-dependent Exposure Variable in Occupational Disease Study

Moon JD

  • KMID: 2141569
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):201-207.
Although the final cumulative exposure has been used as a exposure variable on the cohort study for the relation between exposure and disease, the bias from the use of fixed...
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Effect of Cadmium on Cytokine Gene Expression in a Human Monocytic Cell Line, THP-1

Kang MJ, Yang SH, Chung IS, Shin DH, Park KK, Suh SK

  • KMID: 2141581
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):320-331.
Cadmium, a potent toxic metal, poses a serious environmental threat but the mechanism of its toxicity remains unclear. Also, cadmium is a known immunotoxic agent in animal studies and induces...
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The Stress Level According to the Working Status in the Migrant Workers

Lee MH, Park CY, Koo JW, Yim HW

  • KMID: 2141580
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):309-319.
The number of foreign workers, which has increased since 1989, can be classified into industrial trainees and illegal migratory workers. As of January 1995, the official number of foreign workers...
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Effect of Noise Exposure and Psychosocial Factors on Blood Pressure in Manufacturing Workers

Cha BS, Koh SB, Chang SJ, Park JK, Kang MG, Koh SY

  • KMID: 2141573
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):244-257.
This study was conducted to assess the effects of noise exposure and psychosocial factor on blood pressure in manufacturing workers. The study subjects are 414 workers (243 males, 171 females)...
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Phototoxic Dermatitis by Coal Tar Containing Paint

Hong YC, Ha EH, Park HS

  • KMID: 2141575
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):267-274.
Many workers who used coal tar containing paints in shipyard industry have dermatitis, but the etiology is not known well. Our research is to fond out the etiology of the...
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Neurobehavioral Effects of Low Level Lead-exposed Workers at CRT(Cathode Ray Tube) Manufacturing Factory

Lee JY, Lee CY, Kim JS, Lee SJ, Park WS, Woo KH

  • KMID: 2141570
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):208-216.
To assess neurobehavioral effects of 48 low level lead-exposed workers in CRT manufacturing factory, simple and choice reaction time test with NTOS (Neurobehavioral Tests for Occupational Screening), digit symbol and...
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A Study of the Correlation Between the Activity of Erythrocyte Pyrimidine 5'-Nucleotidase and Urinary N-Acetyl-beta-D-Glucosaminidase in Lead Exposed Workers

Chang SH, Hwang CH, Lee WJ, Lee SS, Lee BK, Suh HK, Choi JW

  • KMID: 2141574
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):258-266.
In this study, we measured the activity of the erythrocyte pyrimidine 5'-nucleotidase (P5N) and urinary N-acetyl-beta-D-glucosaminidase (NAG) from 154 workers exposed to lead and 43 workers not exposed. We analyzed...
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Effects of the Chelating Agent on the Nephrotoxicity and Histopathological Change in Rat after Administration of Inorganic Mercury

Cha BS, Koh SB, Hong SW

  • KMID: 2141578
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):292-300.
This study was to determine the effects of Sodium-N-[4-methoxybenzyl]-D-glucamine-N-dithiocarbamate(MeOBGDTC) on the nephrotoxicity of mercury and histopathological change in rats pretreated with mercuric chloride 48h earlier. In a firsts experiment, 3...
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The Metabolism and Liver Toxicity of N, N-dimethylformamide in the Isolated Perfused Liver

Koh SB, Cha BS, Kang MG, Koh SY, Lee JW, Kwon SO

  • KMID: 2141571
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):217-229.
N, N-dimethylformamide (DMF) is a solvent which is widely used in the industrial workplace. It causes the liver damages to the chronically exposed workers and is also well known as...
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Neuropsychiatric Symptoms of Workers Exposed to 2-Bromopropane

Choi KS, Chun BY, Park JS, Kim YH, Moon YH

  • KMID: 2141579
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):301-308.
To investigate the impact of 2-bromopropane on neuropsychiatric symptoms, 33 exposed workers and 77 non-exposes workers in electronic company were recruited. Neuropsychiatric symptoms were assessed using self-administered questionnaire. Memory disturbance,...
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Study on the Cervicobrachial Syndrome Among Microwave-oven Assemblers (III) : A Review on Working Posture

Kim YO, Park J, Ryu SY, Lee CG

  • KMID: 2141576
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):275-282.
Working postures in 116 microwave-oven assemblers were measured and analysed using postural load scores of body parts in 137 workers complaining the cervicobrachial syndrome (CBS). The relationship between postural load...
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Biological Indices for Early Detection of Cadmium Poisoning: Significance of Urinary Metallothionein

Park JD, Hong YP, Chang IW

  • KMID: 2141572
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):230-243.
Metallothionein(MT) is a low molecular weight protein that is induced as a defence mechanism for cadmium (Cd) toxicity. In present study, urinary MT was determined using a competitive ELISA in...
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Biomarkers of Susceptibility in Bladder Carcinogenesis

Park SK, Jung HW, Kang DH, Yoo KY, Cho SH

  • KMID: 2141583
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):341-356.
Owing to the development of molecular biological techniques to identify new biomarkers of bladder cancer, the information obtained from the studios in which newly developed biomarkers are applied potentially useful...
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ALDH2 Genetic Polymorphism and Urinary Hippuric Acid Concentration in Toluene Exposed Workers

Kwon OC, Joo R, Lee JJ, Kim CY, Chung JH, Kim SY

  • KMID: 2141582
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):332-340.
In this study we evaluated the effects of the genetic polymorphism of aldehyde dehydrogenase2 (ALDH2) on toluene metabolism and determined biological exposure indices (BEIs) for toluene by the genotypes of...
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